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patiromer (Oral route)


Oral route(Powder for Suspension)

Patiromer binds to many orally administered medications, which could decrease their absorption and reduce their effectiveness. Administer other oral medications at least 6 hours before or 6 hours after patiromer. Choose patiromer or the other oral medication if adequate dosing separation is not possible .

Commonly used brand name(s)

In the U.S.

  • Veltassa

Available Dosage Forms:

  • Powder for Suspension

Therapeutic Class: Exchange Resin

Uses For patiromer

Patiromer is used to treat hyperkalemia (high potassium in the blood). patiromer is a potassium binder. It should not be used as an emergency treatment for life-threatening hyperkalemia.

patiromer is available only with your doctor's prescription.

Before Using patiromer

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For patiromer, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to patiromer or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies have not been performed on the relationship of age to the effects of patiromer in the pediatric population. Safety and efficacy have not been established.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of patiromer in the elderly. However, elderly patients are more likely to have unwanted side effects which may require caution in patients receiving patiromer.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of patiromer. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bowel blockage or
  • Constipation, severe or
  • Impaction (bowel movement problem)—Use is not recommended in patients with these conditions. patiromer may not work properly and may worsen these conditions.

Proper Use of patiromer

Take patiromer exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

patiromer should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Take patiromer with food. Do not heat patiromer (eg, microwave) or add to heated foods or liquids. Do not take patiromer in its dry form.

To use:

  • Measure 1/3 cup of water. Pour half of the water into a glass.
  • Empty the entire contents of a packet into the glass. You may need more than 1 packet for your prescribed dose.
  • Stir the mixture well.
  • Pour the remaining water into the glass containing the mixture and stir thoroughly. The mixture will look cloudy and the powder will not dissolve. Add more water if the mixture is too thick.
  • Drink the mixture immediately.
  • If some powder remains in the glass, add more water, stir, and drink immediately. Repeat as needed to make sure you get your full dose.

If you are taking other medicines, use Veltassa™ 6 hours before or 6 hours after these medicines. Veltassa™ may keep other medicines from working properly.


The dose of patiromer will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of patiromer. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (powder for suspension):
    • For treatment of hyperkalemia:
      • Adults—At first, 8.4 grams once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 25.2 grams once a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of patiromer, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in the refrigerator. You may store the medicine at room temperature and must be used within 3 months of being taken out of the refrigerator.

Precautions While Using patiromer

It is very important that your doctor check your progress at regular visits to make sure that patiromer is working properly. Blood tests may be needed to check for unwanted effects.

patiromer may cause hypomagnesemia (low magnesium levels in the blood). Check with your doctor right away if you have drowsiness, loss of appetite, mood or mental changes, muscle spasms (tetany) or twitching, seizures, nausea or vomiting, trembling, or unusual tiredness or weakness.

patiromer Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Drowsiness
  • loss of appetite
  • mood or mental changes
  • muscle spasms (tetany) or twitching
  • nausea or vomiting
  • seizures
  • trembling
  • unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Difficulty having a bowel movement (stool)
Less common
  • Abdominal or stomach discomfort
  • bloated or full feeling
  • diarrhea
  • excess air or gas in the stomach or intestines
  • passing gas

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

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