Skip to Content

OptiPranolol Side Effects

Generic Name: metipranolol ophthalmic

Note: This page contains side effects data for the generic drug metipranolol ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name OptiPranolol.

For the Consumer

Applies to metipranolol ophthalmic: ophthalmic solution

As well as its needed effects, metipranolol ophthalmic (the active ingredient contained in OptiPranolol) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking metipranolol ophthalmic, check with your doctor immediately:

Incidence not determined
  • Bloody nose
  • blurred vision
  • burning, dry, or itching eyes
  • changes in vision
  • chest pain or discomfort
  • cough producing mucus
  • difficult or labored breathing
  • difficulty in moving
  • difficulty seeing at night
  • difficulty swallowing
  • discharge, excessive tearing
  • fast, slow, irregular, pounding, or racing heartbeat or pulse
  • headache
  • hives
  • increased sensitivity of eyes to sunlight
  • itching
  • lightheadedness, dizziness, or fainting
  • muscle pain or stiffness
  • nausea
  • nervousness
  • pain in forehead
  • pain or discomfort in arms, jaw, back, or neck
  • pain, swelling, or redness in joints
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness, pain, swelling, or itching of the eye, eyelid, or inner lining of eyelid
  • shortness of breath
  • skin rash
  • sweating
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing
  • vomiting

If any of the following symptoms of overdose occur while taking metipranolol ophthalmic, get emergency help immediately:

Symptoms of overdose:
  • Confusion
  • dilated neck veins
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • extreme fatigue
  • irregular breathing
  • swelling of face, fingers, feet, or lower legs
  • weight gain

Minor Side Effects

Some metipranolol ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not determined
  • Discouragement
  • feeling sad or empty
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle aching or cramping
  • runny nose
  • sleepiness or unusual drowsiness
  • sneezing
  • stuffy nose
  • tiredness
  • trouble concentrating
  • trouble sleeping

For Healthcare Professionals

Applies to metipranolol ophthalmic: ophthalmic solution


The most commonly reported side effects were abnormal vision, blurred vision, conjunctivitis, and tearing.[Ref]


Frequency not reported: Abnormal vision, blepharitis, blurred vision, browache, conjunctivitis, edema, eyelid dermatitis, photophobia, tearing, uveitis, eye discomfort[Ref]


Frequency not reported: Angina, atrial fibrillation, bradycardia, hypertension, palpitation, myocardial infarct[Ref]


Frequency not reported: Bronchitis, coughing, dyspnea, epistaxis, rhinitis[Ref]

Nervous system

Frequency not reported: Dizziness, headache, nervousness, somnolence[Ref]


Frequency not reported: Allergic reaction[Ref]


Frequency not reported: Anxiety, depression[Ref]


Frequency not reported: Arthritis, myalgia[Ref]


Frequency not reported: Asthenia[Ref]


Frequency not reported: Nausea[Ref]


Frequency not reported: Rash[Ref]


1. "Product Information. OptiPranolol (metipranolol)." Bausch and Lomb, Tampa, FL.

It is possible that some side effects of OptiPranolol may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.