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OptiPranolol Side Effects

Generic name: metipranolol ophthalmic

Medically reviewed by Last updated on Jul 9, 2022.

Note: This document contains side effect information about metipranolol ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name OptiPranolol.

For the Consumer

Applies to metipranolol ophthalmic: ophthalmic solution

Side effects requiring immediate medical attention

Along with its needed effects, metipranolol ophthalmic (the active ingredient contained in OptiPranolol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking metipranolol ophthalmic:

Incidence not determined

  • Bloody nose
  • blurred vision
  • burning, dry, or itching eyes
  • changes in vision
  • chest pain or discomfort
  • cough producing mucus
  • difficult or labored breathing
  • difficulty in moving
  • difficulty seeing at night
  • difficulty swallowing
  • discharge, excessive tearing
  • fast, slow, irregular, pounding, or racing heartbeat or pulse
  • headache
  • hives
  • increased sensitivity of eyes to sunlight
  • itching
  • lightheadedness, dizziness, or fainting
  • muscle pain or stiffness
  • nausea
  • nervousness
  • pain in forehead
  • pain or discomfort in arms, jaw, back, or neck
  • pain, swelling, or redness in joints
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness, pain, swelling, or itching of the eye, eyelid, or inner lining of eyelid
  • shortness of breath
  • skin rash
  • sweating
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking metipranolol ophthalmic:

Symptoms of overdose

  • Confusion
  • dilated neck veins
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  • extreme fatigue
  • irregular breathing
  • swelling of face, fingers, feet, or lower legs
  • weight gain

Side effects not requiring immediate medical attention

Some side effects of metipranolol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not determined

  • Discouragement
  • feeling sad or empty
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle aching or cramping
  • runny nose
  • sleepiness or unusual drowsiness
  • sneezing
  • stuffy nose
  • tiredness
  • trouble concentrating
  • trouble sleeping

For Healthcare Professionals

Applies to metipranolol ophthalmic: ophthalmic solution


The most commonly reported side effects were abnormal vision, blurred vision, conjunctivitis, and tearing.[Ref]


Frequency not reported: Abnormal vision, blepharitis, blurred vision, browache, conjunctivitis, edema, eyelid dermatitis, photophobia, tearing, uveitis, eye discomfort[Ref]


Frequency not reported: Angina, atrial fibrillation, bradycardia, hypertension, palpitation, myocardial infarct[Ref]


Frequency not reported: Bronchitis, coughing, dyspnea, epistaxis, rhinitis[Ref]

Nervous system

Frequency not reported: Dizziness, headache, nervousness, somnolence[Ref]


Frequency not reported: Allergic reaction[Ref]


Frequency not reported: Anxiety, depression[Ref]


Frequency not reported: Arthritis, myalgia[Ref]


Frequency not reported: Asthenia[Ref]


Frequency not reported: Nausea[Ref]


Frequency not reported: Rash[Ref]


1. "Product Information. OptiPranolol (metipranolol ophthalmic)." Bausch and Lomb (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.