Notuss-PE Side Effects
Generic name: codeine / phenylephrine
Note: This document contains side effect information about codeine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Notuss-PE.
Respiratory depression has been associated with antitussive use of codeine in young children. Respiratory depression and death have occurred in children who received codeine in the postoperative period following tonsillectomy and/or adenoidectomy. Further investigation has shown these patients to be ultra-rapid metabolizers of codeine. Children with obstructive sleep apnea who are treated with codeine appear to be particularly sensitive to the respiratory depressant effects of codeine.[Ref]
Frequency not reported: Respiratory depression
Frequency not reported: Respiratory distress[Ref]
Frequency not reported: Ischemia[Ref]
Frequency not reported: Rash[Ref]
Frequency not reported: Euphoria, dysphoria, transient hallucination, disorientation
Frequency not reported: CNS depression, lightheadedness, dizziness, sedation, headache, convulsions, weakness
Frequency not reported: Restlessness, dizziness, tremor, weakness[Ref]
Frequency not reported: Visual disturbances[Ref]
Frequency not reported: Pain[Ref]
More about Notuss-PE (codeine / phenylephrine)
Related treatment guides
1. "Product Information. Ala-Hist AC (codeine-phenylephrine)." Poly Pharmaceuticals Inc, Quitman, MS.
2. "Product Information. Promethazine VC with Codeine (codeine / phenylephrine/promethazine)." Par Pharmaceutical Inc (formerly Qualitest Pharmaceuticals Inc), Huntsville, AL.
Some side effects may not be reported. You may report them to the FDA.