Narcof Side Effects

Generic Name: guaifenesin / hydrocodone

Note: This document contains side effect information about guaifenesin / hydrocodone. Some of the dosage forms listed on this page may not apply to the brand name Narcof.

For the Consumer

Applies to guaifenesin/hydrocodone: oral solution

Along with its needed effects, guaifenesin / hydrocodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking guaifenesin / hydrocodone:

Incidence Not Known

• Agitation
• bladder pain
• bloating or swelling of the face, arms, hands, lower legs, or feet
• bloody or cloudy urine
• changes in vision
• chills
• cough
• darkening of the skin
• diarrhea
• difficult, burning, or painful urination
• difficulty swallowing or breathing
• dizziness
• dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
• fainting
• fast heartbeat
• frequent urge to urinate
• hives, itching, skin rash
• irregular, fast or slow, or shallow breathing
• loss of appetite
• loss of consciousness
• mental depression
• nausea
• overactive reflexes
• pains in stomach, side, or abdomen, possibly radiating to the back
• pale or blue lips, fingernails, or skin
• poor coordination
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• rapid weight gain
• restlessness shivering talking or acting with excitement you cannot control
• tightness in the chest
• tingling of the hands or feet
• trembling or shaking twitching
• unusual weight gain or loss
• vomiting
• yellow eyes or skin

Some side effects of guaifenesin / hydrocodone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

• Diarrhea
• difficulty having a bowel movement
• feeling of warmth
• headache
• lack or loss of strength
• nausea
• redness of the face, neck, arms, and occasionally, upper chest
• sleepiness or unusual drowsiness
• stomach pain
• sudden sweating
• trouble sleeping

For Healthcare Professionals

Applies to guaifenesin / hydrocodone: oral capsule, oral liquid, oral syrup, oral tablet, oral tablet extended release

General

The most commonly reported adverse effects have included headache, dizziness, sedation, nausea, diarrhea, decreased blood pressure, and flushing.^[Ref]

Nervous system

Frequency not reported: Sedation (somnolence), headache, dizziness, decreased mental alertness with impaired mental and/or physical abilities

Hydrocodone:

-Increased intracranial pressure^[Ref]

Respiratory

Frequency not reported: Dose-related respiratory depression including fatal respiratory depression^[Ref]

Gastrointestinal

Frequency not reported: Nausea, diarrhea

Hydrocodone:

Frequency not reported: Paralytic ileus^[Ref]

Dermatologic

Frequency not reported: Hot flush^[Ref]

Cardiovascular

Frequency not reported: Decreased blood pressure^[Ref]

Psychiatric

Frequency not reported: Mental clouding, anxiety, fear, dysphoria, drug dependence, mood changes, sleeplessness

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer