Narcof Side Effects
Generic Name: guaifenesin / hydrocodone
Note: This document contains side effect information about guaifenesin / hydrocodone. Some of the dosage forms listed on this page may not apply to the brand name Narcof.
For the Consumer
Applies to guaifenesin / hydrocodone: oral capsule, oral liquid, oral solution, oral syrup, oral tablet, oral tablet extended release
Along with its needed effects, guaifenesin/hydrocodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking guaifenesin / hydrocodone:
Incidence not known- Difficult or troubled breathing
- irregular, fast or slow, or shallow breathing
- pale or blue lips, fingernails, or skin
Some side effects of guaifenesin / hydrocodone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common- Diarrhea
- dizziness
- feeling of warmth
- headache
- nausea
- redness of the face, neck, arms, and occasionally, upper chest
- sleepiness or unusual drowsiness
- sudden sweating
For Healthcare Professionals
Applies to guaifenesin / hydrocodone: oral capsule, oral liquid, oral syrup, oral tablet, oral tablet extended release
General
The most commonly reported adverse effects have included headache, dizziness, sedation, nausea, diarrhea, decreased blood pressure, and flushing.[Ref]
Nervous system
Frequency not reported: Sedation (somnolence), headache, dizziness, decreased mental alertness with impaired mental and/or physical abilities
Hydrocodone:
-Increased intracranial pressure[Ref]
Respiratory
Frequency not reported: Dose-related respiratory depression including fatal respiratory depression[Ref]
Gastrointestinal
Frequency not reported: Nausea, diarrhea
Hydrocodone:
Frequency not reported: Paralytic ileus[Ref]
Dermatologic
Frequency not reported: Hot flush[Ref]
Cardiovascular
Frequency not reported: Decreased blood pressure[Ref]
Psychiatric
Frequency not reported: Mental clouding, anxiety, fear, dysphoria, drug dependence, mood changes, sleeplessness
References
1. Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):
2. "Product Information. Flowtuss (guaifenesin-hydrocodone)." Mission Pharmacal Company, San Antonio, TX.
3. Morrow PL, Faris EC "Death associated with inadvertent hydrocodone overdose in a child with a respiratory tract infection." Am J Forensic Med Pathol 8 (1987): 60-3
4. Turturro MA, Paris PM, Yealy DM, Menegazzi JJ "Hydrocodone versus codeine in acute musculoskeletal pain." Ann Emerg Med 20 (1991): 1100-3
5. Sackner MA "Effects of hydrocodone bitartrate on breathing pattern of patients with chronic obstructive pulmonary disease and restrictive lung disease." Mt Sinai J Med 51 (1984): 222-6
6. "Product Information. Vicodin Tuss (guaifenesin-hydrocodone)" Knoll Pharmaceutical Company, Mount Olive, NJ.
7. "Product Information. Robitussin (guaifenesin)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
8. Fricke J, Halladay SC, Bynum L, Francisco CA "Pain relief after dental impaction surgery using ketorolac, hydrocodone plus acetaminophen, or placebo." Clin Ther 15 (1993): 500-9
9. Sorensen JL, Hargreaves WA, Weinberg JA "Heroin addict responses to six weeks of detoxification with LAAM." Drug Alcohol Depend 9 (1982): 79-87
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about Narcof (guaifenesin / hydrocodone)
- Side Effects
- During Pregnancy
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: upper respiratory combinations
Consumer resources
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