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Mirvaso Side Effects

Generic Name: brimonidine topical

Note: This document contains side effect information about brimonidine topical. Some of the dosage forms listed on this page may not apply to the brand name Mirvaso.

In Summary

Common side effects of Mirvaso include: flushing. Other side effects include: burning sensation of skin and erythema. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to brimonidine topical: topical application gel/jelly

Along with its needed effects, brimonidine topical (the active ingredient contained in Mirvaso) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking brimonidine topical:

More common
  • Flushing or redness of the skin
  • unusually warm skin
Less common
  • Blemishes on the skin
  • blistering, burning, crusting, dryness, or flaking of the skin
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • pimples

Some side effects of brimonidine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • fever
  • headache
  • muscle aches
  • sore throat
  • stuffy or runny nose
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to brimonidine topical: topical gel


The most commonly reported adverse reactions are headache, erythema, pruritus, flushing and skin burning sensation.[Ref]


Common (1% to 10%): Acne, allergic contact dermatitis, contact dermatitis, dermatitis, erythema, pruritus, rosacea, skin burning sensation, skin irritation, skin pain, warm skin
Uncommon (0.1% to 1%): Dry skin, skin discomfort, papular rash
Postmarketing reports: Aggravated erythema, face swelling, pallor, urticaria[Ref]


Common (1% to 10%): Nasal congestion, nasopharyngitis, upper respiratory track infection
Postmarketing reports: Throat tightness[Ref]


Common (1% to 10%): Blurred vision, increased intraocular pressure
Uncommon (0.1% to 1%): Eyelid edema[Ref]

Nervous system

Common (1% to 10%): Headache, paresthesia
Postmarketing reports: Dizziness[Ref]


Common (1% to 10%): Flushing
Postmarketing reports: Bradycardia, hypotension, orthostatic hypotension[Ref]


Uncommon (0.1% to 1%): Feeling hot, peripheral coldness[Ref]


Uncommon (0.1% to 1%): Dry mouth
Postmarketing reports: Lip swelling, tongue swelling[Ref]


Postmarketing reports: Angioedema, hypersensitivity[Ref]


Postmarketing reports: Application site pallor, excessive whitening at application site[Ref]


1. "Product Information. Mirvaso (brimonidine topical)." Galderma Laboratories Inc, Cranbury, NJ.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of Mirvaso may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.