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Lodoxamide ophthalmic Side Effects

For the Consumer

Applies to lodoxamide ophthalmic: ophthalmic solution

Side Effects of This Medicine

In addition to its needed effects, some unwanted effects may be caused by lodoxamide ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking lodoxamide ophthalmic, check with your doctor or nurse as soon as possible:

Less common:
  • Blurred vision
  • feeling of something in eye, itching, discomfort, redness, tearing or discharge, or other eye or eyelid irritation (not present before you started using this medicine or becoming worse while you are using this medicine)
  • Dizziness
  • mucus from eye, eye pain, or swelling of eye or eyelid (not present before you started using this medicine or becoming worse while you are using this medicine)
  • headache
  • sensitivity of eyes to light
  • skin rash

Minor Side Effects

Some of the side effects that can occur with lodoxamide ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Burning or stinging (when medicine is applied)
Less common or rare:
  • Aching eyes
  • crusting in corner of eye or on eyelid
  • drowsiness or sleepiness
  • dryness of nose or eyes
  • feeling of heat in eye
  • heat sensation on body
  • nausea or stomach discomfort
  • scales on eyelid or eyelash
  • sneezing
  • sticky feeling of eyes
  • tired eyes

For Healthcare Professionals

Applies to lodoxamide ophthalmic: ophthalmic solution


The most common ocular side effects reported were a burning sensation, stinging or discomfort following instillation.[Ref]


Very common (10% or more): Discomfort upon instillation (15%)
Common (1% to 10%): Blurred vision, dryness, pruritus, increased lacrimation, hyperemia
Uncommon (0.1% to 1%): Eye pain, edema, asthenopia, corneal deposits, abnormal or foreign body sensation in eye, discharge, irritation, eyelid exfoliation, lid margin crusting
Rare (0.01% to 0.1%): Corneal erosion, scar, abrasion, epitheliopathy; anterior chamber cell, keratitis, blepharitis, allergy, visual impairment, eyelid edema, conjunctival disorder
Very rare: Fatigue, warming sensation, keratopathy, keratitis, blepharitis, sticky sensation, corneal abrasion[Ref]


Uncommon (0.1% to 1%): Nausea
Rare (0.01% to 0.1%): Abdominal discomfort[Ref]

Nervous system

Common (1% to 10%): Headache
Uncommon (0.1% to 1%): Dizziness
Rare (0.01% to 0.1%): Somnolence, dysgeusia[Ref]


Rare (0.01% to 0.1%): Nasal dryness, sneezing[Ref]


Frequency not reported: Palpitations[Ref]


Uncommon (0.1% to 1%): Feeling hot[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Alomide (lodoxamide ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

Not all side effects for lodoxamide ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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