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Lodoxamide ophthalmic Side Effects

Medically reviewed by Last updated on Nov 3, 2022.

Applies to lodoxamide ophthalmic: ophthalmic solution.

Side Effects of This Medicine

Serious side effects

Along with its needed effects, lodoxamide ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking lodoxamide ophthalmic:

Less common

  • Blurred vision
  • feeling of something in eye, itching, discomfort, redness, tearing or discharge, or other eye or eyelid irritation (not present before you started using this medicine or becoming worse while you are using this medicine)


  • Dizziness
  • mucus from eye, eye pain, or swelling of eye or eyelid (not present before you started using this medicine or becoming worse while you are using this medicine)
  • headache
  • sensitivity of eyes to light
  • skin rash

Other side effects

Some side effects of lodoxamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning or stinging (when medicine is applied)

Less common or rare

  • Aching eyes
  • crusting in corner of eye or on eyelid
  • drowsiness or sleepiness
  • dryness of nose or eyes
  • feeling of heat in eye
  • heat sensation on body
  • nausea or stomach discomfort
  • scales on eyelid or eyelash
  • sneezing
  • sticky feeling of eyes
  • tired eyes

For Healthcare Professionals

Applies to lodoxamide ophthalmic: ophthalmic solution.


The most common ocular side effects reported were a burning sensation, stinging or discomfort following instillation.[Ref]


Very common (10% or more): Discomfort upon instillation (15%)

Common (1% to 10%): Blurred vision, dryness, pruritus, increased lacrimation, hyperemia

Uncommon (0.1% to 1%): Eye pain, edema, asthenopia, corneal deposits, abnormal or foreign body sensation in eye, discharge, irritation, eyelid exfoliation, lid margin crusting

Rare (0.01% to 0.1%): Corneal erosion, scar, abrasion, epitheliopathy; anterior chamber cell, keratitis, blepharitis, allergy, visual impairment, eyelid edema, conjunctival disorder

Very rare: Fatigue, warming sensation, keratopathy, keratitis, blepharitis, sticky sensation, corneal abrasion[Ref]


Uncommon (0.1% to 1%): Nausea

Rare (0.01% to 0.1%): Abdominal discomfort[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness

Rare (0.01% to 0.1%): Somnolence, dysgeusia[Ref]


Rare (0.01% to 0.1%): Nasal dryness, sneezing[Ref]


Frequency not reported: Palpitations[Ref]


Uncommon (0.1% to 1%): Feeling hot[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Alomide (lodoxamide ophthalmic)." Alcon Laboratories Inc (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.