Econazole Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 20, 2024.

Applies to econazole topical: topical cream, topical foam.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and check you for any problems or unwanted effects that may be caused by this medicine.

Do not use this medicine for a skin problem that has not been checked by your doctor.

If your skin problem does not improve within 2 weeks or more, or if it becomes worse, check with your doctor.

Check with your doctor right away if you have a skin rash, burning, stinging, swelling, redness, or irritation on the skin.

Good health habits are also required for patients using this medicine to help clear up your infection completely and to help make sure it does not return.

For patients using the cream for athlete's foot (tinea pedis; ringworm of the foot), the following instructions will help keep the feet cool and dry:

• Carefully dry the feet, especially between the toes, after bathing.
• Avoid wearing socks made from wool or synthetic materials (eg, rayon or nylon). Instead, wear clean, cotton socks and change them daily or more often if your feet sweat a lot.
• Wear sandals or well-ventilated shoes (eg, shoes with holes).
• Use a bland, absorbent powder (eg, talcum powder) or an antifungal powder (eg, tolnaftate) between the toes, on the feet, and in socks and shoes one or two times a day. It is best to use the powder between the times you use the cream.
• If you have any questions about these instructions, check with your doctor.

For patients using the cream for ringworm of the groin (tinea cruris; jock itch), the following instructions will help reduce chafing and irritation and will also help keep the groin area cool and dry:

• Avoid wearing underwear that is tight-fitting or made from synthetic materials (eg, rayon or nylon). Instead, wear loose-fitting, cotton underwear.
• Use a bland, absorbent powder (eg, talcum powder) or an antifungal powder (eg, tolnaftate) on the skin. It is best to use the powder between the times you use the cream.
• If you have any questions about these instructions, check with your doctor.

Serious side effects of econazole topical

Along with its needed effects, econazole topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking econazole topical:

For healthcare professionals

Applies to econazole topical: compounding powder, topical cream, topical foam.

Dermatologic adverse events

Topical Cream:

• Common (1% to 10%): Pruritus/itching, skin burning sensation/burning, erythema
• Frequency not reported: Pruritic rash
• Postmarketing reports: Angioedema, contact dermatitis, rash, urticaria, blister, skin exfoliation

Vaginal Cream and Pessaries:

• Common (1% to 10%): Pruritus, skin burning sensation
• Uncommon (0.1% to 1%): Rash
• Rare (0.01% to 0.1%): Erythema
• Postmarketing reports: Angioedema, urticaria, contact dermatitis, skin exfoliation^[Ref]

Other

Topical Cream:

• Common (1% to 10%): Pain/stinging
• Uncommon (0.1% to 1%): Discomfort, swelling^[Ref]

Genitourinary

Vaginal Cream and Pessaries:

• Uncommon (0.1% to 1%): Vulvovaginal burning sensation^[Ref]

Local

Topical Cream:

• Frequency not reported: Lesions with vesiculation at site of application

Topical Foam:

• Uncommon (0.1% to 1%): Application site reactions

Vaginal Cream and Pessaries:

• Postmarketing reports: Application site pain, application site irritation, application site swelling^[Ref]

One patient developed erythematous, edematous, urticarial-like lesions with vesiculation at the site of drug application. Sensitivity to this drug was confirmed by patch testing.^[Ref]

Hypersensitivity

Topical Cream:

• Frequency not reported: Drug sensitivity
• Postmarketing reports: Hypersensitivity

Vaginal Cream and Pessaries:

• Postmarketing reports: Hypersensitivity^[Ref]

See also:

Further information

Econazole topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer