Dopamine Side Effects
For the Consumer
Applies to dopamine: parenteral injection concentrate for iv infusion, parenteral injection for iv infusion
Side effects include:
Dopamine may cause cardiac conduction abnormalities (e.g., ventricular arrhythmia, atrial fibrillation, widened QRS complex, ectopic heartbeats), tachycardia, angina, palpitation, bradycardia, vasoconstriction, hypotension, hypertension, dyspnea, nausea, vomiting, headache, anxiety, azotemia, piloerection, and gangrene of the extremities.
For Healthcare Professionals
Applies to dopamine: intravenous solution
Gangrene of the feet occurred in patients with preexisting vascular disorders and/or at doses of at least 10 to 14 mcg/kg/min given for prolonged periods of time.
Ventricular arrhythmias occurred at very high doses.[Ref]
Common (1% to 10%): Ectopic beats, tachycardia, anginal pain, palpitation, hypotension, vasoconstriction
Uncommon (0.1% to 1%): Aberrant ventricular conduction/ventricular arrhythmia, bradycardia, widened QRS complex, hypertension
Frequency not reported: Gangrene of the feet/extremities, peripheral cyanosis, fatal ventricular arrhythmias, atrial fibrillation, cardiac conduction abnormalities[Ref]
Common (1% to 10%): Nausea, vomiting[Ref]
Common (1% to 10%): Headache[Ref]
Common (1% to 10%): Dyspnea[Ref]
Very rare (less than 0.01%): Gangrene
Frequency not reported: Piloerection[Ref]
Necrosis and tissue sloughing may be caused by extravasation of this drug.[Ref]
Frequency not reported: Necrosis, tissue sloughing, local ischemia and vasoconstriction[Ref]
Frequency not reported: Anxiety[Ref]
Frequency not reported: Azotemia[Ref]
Frequency not reported: Mydriasis[Ref]
Frequency not reported: Hypovolemia[Ref]
1. "Product Information. Intropin (dopamine)." DuPont Pharmaceuticals, Wilmington, DE.
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Some side effects of dopamine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
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- Drug class: catecholamines
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