Diclofenac / lidocaine topical Side Effects
Applies to diclofenac/lidocaine topical: topical film, topical gel.
Warning
Diclofenac and lidocaine topical can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diclofenac and lidocaine topical may also cause stomach or intestinal bleeding, which can be fatal.
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Stop using diclofenac and lidocaine topical and call your doctor at once if you have:
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pale, gray, or blue colored skin, headache, rapid heart rate, shortness of breath, feeling light-headed, or tired.
Common side effects may include:
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pain, burning, irritation, or skin changes where the medicine was applied.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to diclofenac / lidocaine topical: topical film, topical gel.
Cardiovascular
Frequency not reported: Bradycardia, hypotension, cardiovascular collapse, cardiac arrest
Postmarketing reports: Flushing[Ref]
Dermatologic
Frequency not reported: Blisters, bruising, depigmentation, dermatitis, discoloration, erythema, exfoliation, petechia, pruritus, vesicles[Ref]
Gastrointestinal
Postmarketing reports: Nausea, vomiting[Ref]
General
The most reported adverse reactions were application site reactions, which were mild and transient, and resolved spontaneously within a few minutes to hours.[Ref]
Local
Frequency not reported: Irritation, papules[Ref]
Metabolic
Frequency not reported: Edema[Ref]
Musculoskeletal
Frequency not reported: Twitching[Ref]
Nervous system
Frequency not reported: Burning sensation, abnormal sensation, drowsiness, convulsions, unconsciousness
Postmarketing reports: Dizziness, headache, hyperesthesia, hypoesthesia, light headedness, metallic taste, paresthesia, somnolence, taste alteration, tremors[Ref]
Sensations of heat, cold, or numbness were reported.[Ref]
Ocular
Postmarketing reports: Visual disturbances[Ref]
Visual disturbances such as blurred vision was reported.[Ref]
Other
Postmarketing reports: Asthenia, pain exacerbated, tinnitus[Ref]
Psychiatric
Frequency not reported: Apprehension, euphoria
Postmarketing reports: Confusion, disorientation, nervousness[Ref]
Respiratory
Frequency not reported: Respiratory depression, respiratory arrest[Ref]
More about diclofenac / lidocaine topical
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- Drug class: topical non-steroidal anti-inflammatories
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References
1. Product Information. Diclona (diclofenac-lidocaine topical). Terrain Pharmaceuticals. 2022;1.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
