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Dexamethasone / tobramycin ophthalmic Side Effects

Medically reviewed by Last updated on Nov 14, 2023.

Applies to dexamethasone/tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension.

Serious side effects

Along with its needed effects, dexamethasone/tobramycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking dexamethasone / tobramycin ophthalmic:

Less common


For Healthcare Professionals

Applies to dexamethasone / tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension.


Frequency not reported: Hypersensitivity[Ref]


Uncommon (0.1% to 1%): Eye pain, eye pruritus, ocular discomfort, ocular hypertension, conjunctival edema, increased intraocular pressure, eye irritation

Rare (less than 0.1%): Keratitis, eye allergy, blurred vision, dry eye, ocular hyperemia

Frequency not reported: Eyelid edema, erythema of the eyelid, mydriasis, increased lacrimation


-Common (1% to 10%): Ocular hyperemia, erythema of eyelid, abnormal sensation in eye, eye pain

-Uncommon (0.1% to 1%): Eye pruritus, ocular discomfort, eye allergy, eyelid edema, conjunctivitis, glare, increased lacrimation, keratitis

-Frequency not reported: Optic nerve damage, posterior subcapsular cataract formation, fungal infections of the cornea, bacterial ocular infection


-Common (1% to 10%):

-Frequency not reported: Conjunctival erythema, ocular toxicity[Ref]


Frequency not reported: Swelling face[Ref]


Frequency not reported: Rash, pruritus[Ref]


The most commonly reported side effects were eye irritation, ocular hyperemia, erythema of eyelid, abnormal sensation in eye, ocular hyperemia, and eye pain.[Ref]


Rare (less than 0.1%): Dysgeusia

Frequency not reported: Nausea, abdominal discomfort[Ref]



-Frequency not reported: Delayed wound healing[Ref]

Nervous system

Uncommon (0.1% to 1%): Headache

Frequency not reported: Dizziness[Ref]


Uncommon (0.1% to 1%): Rhinorrhea, laryngospasm[Ref]


1. Product Information. Tobradex (dexamethasone-tobramycin ophthalmic). Alcon Laboratories Inc. 2001;PROD.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.