Dexamethasone / Tobramycin Ophthalmic Dosage

Usual Adult Dose for Uveitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Adult Dose for Bacterial Conjunctivitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Adult Dose for Keratitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Uveitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Bacterial Conjunctivitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Keratitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-This drug is for topical use only and not for injection or oral use.
-Ointment: The manufacturer product information should be consulted.

Patient advice:
-Do not touch dropper tip to any surface, as this may contaminate the contents.
-Contact lenses should not be worn during the use of this product.