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Dexamethasone / Tobramycin Ophthalmic Dosage

Medically reviewed on December 15, 2017.

Applies to the following strengths: 0.1%-0.3%; 0.05%-0.3%

Usual Adult Dose for Uveitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Adult Dose for Bacterial Conjunctivitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Adult Dose for Keratitis

Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Uveitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Bacterial Conjunctivitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Usual Pediatric Dose for Keratitis

2 years or older:
Suspension: 1 or 2 drops into the conjunctival sac(s) every 4 to 6 hours
Ointment: Apply a small amount (approximately 1/2 inch ribbon) into the conjunctival sac(s) up to 3 or 4 times per day

Comments:
SUSPENSION:
-During the initial 24 to 48 hours, the dosage may be increased to 1 or 2 drops every 2 hours.
-Frequency should be decreased gradually as indicated by improvement in clinical signs.
-No more than 20 mL should be prescribed initially and the prescription should not be refilled without additional evaluation.
OINTMENT:
-No more than 8 g should be prescribed initially and the prescription should not be refilled without further evaluation.

Use: Steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
-This drug is for topical use only and not for injection or oral use.
-Ointment: The manufacturer product information should be consulted.

Patient advice:
-Do not touch dropper tip to any surface, as this may contaminate the contents.
-Contact lenses should not be worn during the use of this product.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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