Collagenase Topical Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 14, 2024.
Applies to collagenase topical: topical application ointment.
Precautions
It is important that your doctor check your progress at regular visits to see if the medicine is working properly.
If your skin problem does not improve or if it becomes worse, check with your doctor.
Serious side effects of collagenase topical
Along with its needed effects, collagenase topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking collagenase topical:
Incidence not known
- chest tightness
- difficulty with swallowing
- dizziness
- fast heartbeat
- fever
- hives, itching, skin rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- redness of the skin
- swelling of the eyelids, face, lips, hands, or feet
- trouble breathing
Other side effects of collagenase topical
Some side effects of collagenase topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- redness around the wound area
For healthcare professionals
Applies to collagenase topical: compounding powder, topical ointment.
General adverse events
The most commonly reported side effect was erythema.[Ref]
Hypersensitivity
- Frequency not reported: Systemic manifestations of hypersensitivity (in a patient treated for more than one year with a combination of collagenase and cortisone)[Ref]
Dermatologic
- Frequency not reported: Erythema[Ref]
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References
1. (2002) "Product Information. Santyl (collagenase topical)." Knoll Pharmaceutical Company
More about collagenase topical
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- Drug class: topical debriding agents
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Further information
Collagenase topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.