Chlorcyclizine / Pseudoephedrine Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 31, 2025.
Applies to chlorcyclizine / pseudoephedrine: oral tablet.
Important warnings
This medicine can cause some serious health issues
Do not use chlorcyclizine and pseudoephedrine if you have used an MAO inhibitor in the past 14 days.
A dangerous drug interaction could occur.
MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorcyclizine / pseudoephedrine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
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fast or uneven heart rate;
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tremor, seizure (convulsions);
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urinating less than usual or not at all; or
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dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).
Common side effects may include:
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dizziness, drowsiness;
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constipation;
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blurred vision; or
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feeling nervous or restless.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
More about chlorcyclizine / pseudoephedrine
- Check interactions
- Compare alternatives
- Dosage information
- Drug class: upper respiratory combinations
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Further information
Chlorcyclizine/pseudoephedrine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.