Bromfenac Side Effects
Applies to bromfenac: oral capsule
Gastrointestinal side effects have frequently included dyspepsia (12%), abdominal pain, constipation, diarrhea, eructation, flatulence, liver enzyme elevations (less than 3 times the upper limit of normal), nausea, and vomiting. Anorexia, colitis, dry mouth, gastritis, gastroenteritis, gastrointestinal hemorrhage, increased appetite, liver test abnormalities, (less or equal to 3 times the upper limit of normal), pancreatitis, peptic ulcer, periodontal abscess, positive fecal occult blood test, rectal disorder, stomatitis, and tenesmus have also been reported (<1%).[Ref]
Nervous system side effects have included dizziness and somnolence. Abnormal dreams, amnesia, anxiety, confusion, depression, emotional lability, euphoria, hallucination, incoordination, insomnia, increased libido, nervousness, paresthesia, psychosis, tremor, and twitching have also been reported (<1%).[Ref]
General effects have frequently included asthenia and headache. Back pain, chest pain, chills, face edema, fever, flu syndrome, generalized edema, infection, and malaise have also been reported (<1%).[Ref]
Endocrine effects have included glycosuria (<1%).[Ref]
Hematologic side effects have included anemia, ecchymosis, and leukopenia (<1%).[Ref]
Musculoskeletal side effects have included leg cramps and myalgia (<1%).[Ref]
Genitourinary side effects have included albuminuria, breast pain, dysuria, hematuria, impotence, menstrual disorder, nocturia, oliguria, orchitis, polyuria, pyuria, enlarged uterine fibroids, urinary frequency, uterine hemorrhage, urinary incontinence, and urinary tract infection (<1%).[Ref]
1. Cohen A "Gastrointestinal blood loss induced by bromfenac sodium, aspirin, and placebo." Clin Ther 17 (1995): 1110-7
2. "Product Information. Duract (bromfenac)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Some side effects may not be reported. You may report them to the FDA.