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Benzamycin Side Effects

Generic Name: benzoyl peroxide / erythromycin topical

Note: This page contains information about the side effects of benzoyl peroxide / erythromycin topical. Some of the dosage forms included on this document may not apply to the brand name Benzamycin.

For the Consumer

Applies to benzoyl peroxide / erythromycin topical: topical gel/jelly

In addition to its needed effects, some unwanted effects may be caused by benzoyl peroxide / erythromycin topical. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking benzoyl peroxide / erythromycin topical:

Less common or rare:
  • Burning, blistering, crusting, itching, severe redness, or swelling of the skin
  • dryness or peeling of the skin
  • eye irritation
  • feeling of warmth, mild stinging, or redness of the skin
  • increased sensitivity of the skin to sunlight
  • oiliness or tenderness of the skin
  • painful irritation of the skin
  • redness or other discoloration of the skin
  • redness, swelling, or itching of the eyelid
  • severe sunburn
  • skin rash
  • swelling of the eyes, face, and nose

For Healthcare Professionals

Applies to benzoyl peroxide / erythromycin topical: topical gel


Local effects are the most commonly reported adverse effects of benzoyl peroxide-erythromycin topical. Transient drying occurs most often, followed by erythema, pruritus, burning, tenderness, and desquamation. A single case of generalized urticarial reaction to erythromycin topical has been reported.[Ref]


Allergic sensitization to benzoyl peroxide has been reported to occur in 1% to 5% of patients.[Ref]


1. "Product Information. Benzamycin Topical Gel (benzoyl peroxide-erythromycin topical)" Dermik Laboratories, Collegeville, PA.

Not all side effects for Benzamycin may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about Benzamycin (benzoyl peroxide / erythromycin topical)

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