Avacopan Side Effects
Medically reviewed by Drugs.com. Last updated on Oct 19, 2022.
Applies to avacopan: oral capsule.
Serious side effects of Avacopan
Along with its needed effects, avacopan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking avacopan:
More common
- Bladder pain
- bloody or cloudy urine
- chest pain or tightness
- cough
- dark urine
- difficult, burning, or painful urination
- fever or chills
- frequent urge to urinate
- loss of appetite
- lower back or side pain
- nausea or vomiting
- sneezing
- sore throat
- stomach pain, severe
- trouble breathing
- unusual tiredness or weakness
- yellow eyes or skin
Less common
- Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
Other side effects of Avacopan
Some side effects of avacopan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- diarrhea
- dizziness
- headache
- skin rash
For Healthcare Professionals
Applies to avacopan: oral capsule.
Musculoskeletal
Common (1% to 10%): Increased creatine phosphokinase[Ref]
Genitourinary
Common (1% to 10%): Urinary tract infection[Ref]
Hepatic
Very common (10% or more): Hepatic-related adverse reactions, including hepatobiliary adverse reactions and liver enzymes abnormalities (13.3%)
Common (1% to 10%): Transaminase elevations[Ref]
Respiratory
Common (1% to 10%): Pneumonia[Ref]
General
The most frequent serious adverse reactions reported have included pneumonia, acute kidney injury, and urinary tract infection.[Ref]
Nervous system
Very common (10% or more): Headache (20.5%), fatigue (10.2%)
Common (1% to 10%): Dizziness, paresthesia[Ref]
Renal
Common (1% to 10%): Acute kidney injury, increased serum creatinine[Ref]
Cardiovascular
Very common (10% or more): Hypertension (18.1%)[Ref]
Dermatologic
Very common (10% or more): Rash (11.4 %)
Common (1% to 10%): Angioedema[Ref]
Gastrointestinal
Very common (10% or more): Diarrhea (15.1%), nausea (23.5%), vomiting (15.1%)
Common (1% to 10%): Upper abdominal pain[Ref]
More about avacopan
- Check interactions
- Reviews (1)
- Dosage information
- During pregnancy
- Drug class: selective immunosuppressants
- En español
Patient resources
Other brands
Professional resources
Related treatment guides
References
1. "Product Information. Tavneos (avacopan)." ChemoCentryx, Inc. (2021):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.