No information is available on the clinical use of avacopan during breastfeeding. Because avacopan is over 99% bound to plasma proteins, the amount in milk is likely to be low. If the mother an older infant requires avacopan, it is not a reason to discontinue breastfeeding. but until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Avacopan
CAS Registry Number
1346623-17-3
Drug Class
Breast Feeding
Lactation
Milk, Human
Antirheumatic Agents
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