Aminolevulinic acid topical Side Effects
Commonly reported side effects of aminolevulinic acid topical include: pruritus, hyperpigmentation, skin erosion, hypopigmentation, and desquamation. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to aminolevulinic acid topical: topical kit, topical solution, topical stick
In addition to its needed effects, some unwanted effects may be caused by aminolevulinic acid topical. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking aminolevulinic acid topical:Less common:
Some of the side effects that can occur with aminolevulinic acid topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Burning, crawling, itching, numbness, prickling, “pins and needles,” stinging, or tingling feelings
- darkening of treated skin
- lightening of treated skin
- scaling or crusting
- skin sore
- small red raised itchy bumps
- swelling of skin
- open sore on skin
- pus filled blister or pimple
- raw skin
For Healthcare Professionals
Applies to aminolevulinic acid topical: topical gel, topical solution
The most commonly reported side effects were scaling/crusting, hypo-/hyper-pigmentation, and itching.[Ref]
Very common (10% or more): Scaling/Crusting (up to 71%), hypo-/hyper-pigmentation (up to 36%), erosion (up to 14%), itching (up to 25%), pruritus
Common (1% to 10%): Wheal/flare, skin disorders NOS, ulceration, bleeding/hemorrhage, vesiculation, pustules, dysesthesia, scabbing, excoriation, oozing, skin tightness
Uncommon (0.1% to 1%): Pustular rash, dry skin, petechiae, hyperkeratosis[Ref]
Very Common (10% or more): Irritation, erythema, pain, edema, exfoliation, induration
Common (1% to 10%): Pain, tenderness, ulceration
Uncommon (0.1% to 1%): Discharge, discoloration, ulcer, chills, feeling hot, pyrexia, wound secretion
Common (1% to 10%): Headache, paraesthesia, hyperalgesia[Ref]
Uncommon (0.1% to 1%): Eyelid edema[Ref]
Uncommon (0.1% to 1%): Nervousness[Ref]
1. "Product Information. Levulan Kerastick (aminolevulinic acid)" Berlex, Richmond, CA.
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Not all side effects for aminolevulinic acid topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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