Alecensa Side Effects
Generic name: alectinib
Medically reviewed by Drugs.com. Last updated on June 28, 2020.
Note: This document contains side effect information about alectinib. Some of the dosage forms listed on this page may not apply to the brand name Alecensa.
Common side effects of Alecensa include: cough, dyspnea, increased creatine phosphokinase in blood specimen, increased serum aspartate aminotransferase, musculoskeletal pain, and myalgia. Other side effects include: bradycardia, and increased serum bilirubin. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to alectinib: oral capsule
Side effects requiring immediate medical attention
Along with its needed effects, alectinib (the active ingredient contained in Alecensa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking alectinib:
- Bloody urine
- chest pain or discomfort
- decreased frequency or amount of urine
- difficulty with moving
- increased blood pressure
- increased thirst
- joint pain or swelling
- loss of appetite
- lower back or side pain
- lightheadedness, dizziness, or fainting
- muscle aching or cramping
- muscle pains or stiffness
- slow or irregular heartbeat
- swelling of the face, fingers, or lower legs
- troubled breathing
- unusual tiredness or weakness
- weight gain
- Clay-colored stools
- dark urine
- decreased appetite
- itching or skin rash
- stomach pain or tenderness
- yellow eyes or skin
- Difficulty breathing
Side effects not requiring immediate medical attention
Some side effects of alectinib may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Back pain
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blurred vision
- difficulty having a bowel movement
- double vision
- lack or loss of strength
- rapid weight gain
- rash with flat lesions or small raised lesions on the skin
- seeing double
- seeing floating dark spots or material before the eyes
- swelling around the eyes
- tingling of the hands or feet
- unusual weight gain or loss
- vision changes
- Change in taste
- loss of taste
For Healthcare Professionals
Applies to alectinib: oral capsule
Very common (10% or more): Increased CPK (43%), myalgia/musculoskeletal pain (29%), back pain (12%), back pain (12%)[Ref]
Very common (10% or more): Increased creatinine (e.g., increased blood creatinine, creatinine renal clearance decreased, glomerular filtration rate decreased, acute kidney injury) (28%)[Ref]
Very common (10% or more): Rash (e.g., acneiform dermatitis, erythema, and different types of rash [macular, papular, maculopapular, generalized, and pruritic]) (15%)
Common (1% to 10%): Photosensitivity[Ref]
Very common (10% or more): Headache (17%)
Common (1% to 10%): Dysgeusia/hypogeusia[Ref]
Very common (10% or more): Cough (19%), dyspnea (16%)
Uncommon (0.1% to 1%): Interstitial lung disease[Ref]
Very common (10% or more): Vision disorder (e.g., blurred vision, vitreous floaters, visual impairment, reduced visual acuity, asthenopia, diplopia) (10%)[Ref]
1. "Product Information. Alecensa (alectinib)." Genentech, South San Francisco, CA.
Frequently asked questions
- How long do you take it for?
- How effective is it for ALK-positive NSCLC?
- How does it work?
- What is Alecensa used to treat?
More about Alecensa (alectinib)
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: multikinase inhibitors
- FDA Approval History
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.