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Medically reviewed by Last updated on Mar 29, 2020.


(LAK ti tol)

Index Terms

  • Lactitol Monohydrate
  • Pizensy

Pharmacologic Category

  • Ammonium Detoxicant
  • Laxative, Osmotic

Use: Labeled Indications

Chronic idiopathic constipation: Treatment of chronic idiopathic constipation (CIC) in adult patients.

Off Label Uses

Portal systemic encephalopathy: Management of acute and chronic portal systemic encephalopathy (hepatic coma).


Mechanical GI obstruction (known or suspected); galactosemia

Drug Interactions

Dichlorphenamide: Laxatives may enhance the hypokalemic effect of Dichlorphenamide. Monitor therapy

Adverse Reactions

1% to 10%:

Cardiovascular: Increased blood pressure (3%)

Gastrointestinal: Flatulence (8%), diarrhea (4%), abdominal distention (3%), abdominal pain (3%), severe diarrhea (1%)

Genitourinary: Urinary tract infection (5%)

Neuromuscular & skeletal: Increased creatine phosphokinase in blood specimen (4%)

Respiratory: Upper respiratory tract infection (9%)

Postmarketing: Hypersensitivity reaction, pruritus, skin rash

Patient Education

What is this drug used for?

• It is used to treat constipation.

Frequently reported side effects of this drug

• Passing gas

• Common cold symptoms

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Persistent diarrhea

• A significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.

Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about lactitol

Professional resources

Other brands: Pizensy

Related treatment guides