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Dosage form: solution/ drops
Ingredients: carboxymethylcellulose sodium 5mg in 1mL
Labeler: Allergan, Inc.
NDC Code: 0023-0403

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

REFRESH PLUS® Lubricant Eye Drops

Drug Facts

Active ingredient

Carboxymethylcellulose sodium 0.5%


Eye lubricant

  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun.
  • May be used as a protectant against further irritation.

  • For external use only.
  • To avoid contamination, do not touch tip of container to any surface. Do not reuse. Once opened, discard.
  • Do not touch unit-dose tip to eye.
  • If solution changes color or becomes cloudy, do not use.

Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.


To open, TWIST AND PULL TAB TO REMOVE. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.

*lf used for post-operative (e.g., LASIK) dryness and discomfort, follow your eye doctor's instructions.

Other information
  • Use only if single-use container is intact.
  • Use before expiration date marked on container.
  • Store at 59°-86°F (15°-30°C).

Inactive ingredients

Calcium chloride; magnesium chloride; potassium chloride; purified water; sodium chloride; and sodium lactate.

May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.

Questions or comments?


NDC 0023-0403-30


Lubricant Eye Drops


Immediate, soothing relief
for dry eyes. Also recommended
for LASIK dryness*

30 Single-Use Containers
0.01 fl oz (0.4 mL) each Sterile

carboxymethylcellulose sodium solution/ drops
Product Information
Product TypeHUMAN OTC DRUGItem Code (Source)NDC:0023-0403
Route of AdministrationOPHTHALMICDEA Schedule    
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
carboxymethylcellulose sodium (carboxymethylcellulose) carboxymethylcellulose sodium5 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
calcium chloride 
magnesium chloride 
potassium chloride 
sodium chloride 
sodium lactate 
hydrochloric acid 
sodium hydroxide 
#Item CodePackage Description
1NDC:0023-0403-055 VIAL, SINGLE-USE in 1 CARTON
10.4 mL in 1 VIAL, SINGLE-USE
2NDC:0023-0403-3030 VIAL, SINGLE-USE in 1 CARTON
20.4 mL in 1 VIAL, SINGLE-USE
3NDC:0023-0403-5050 VIAL, SINGLE-USE in 1 CARTON
30.4 mL in 1 VIAL, SINGLE-USE
4NDC:0023-0403-7070 VIAL, SINGLE-USE in 1 CARTON
40.4 mL in 1 VIAL, SINGLE-USE
5NDC:0023-0403-10100 VIAL, SINGLE-USE in 1 CARTON
50.4 mL in 1 VIAL, SINGLE-USE
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
OTC monograph finalpart34910/09/1996
Labeler - Allergan, Inc. (144796497)
Allergan, Inc.362898611MANUFACTURE(0023-0403)
Allergan Pharmaceuticals Ireland219682291MANUFACTURE(0023-0403)

Revised: 12/2014
Allergan, Inc.

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.