The Zazole brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Zazole?
Terconazole is an antifungal medication that fights infections caused by fungus.
Zazole (for use in the vagina) is used to treat vaginal Candida (yeast) infections.
Zazole may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Zazole if you are allergic to it.
Do not use Zazole if you have never had a vaginal yeast infection that has been confirmed by a doctor.
To make sure Zazole is safe for you, tell your doctor if you have:
fever, chills, vomiting;
if you are having vaginal itching or discomfort for the first time; or
if you think you may have been exposed to HIV (human immunodeficiency virus).
It is not known whether Zazole will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether terconazole vaginal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Do not give this medication to anyone under 18 years old without medical advice.
How should I use Zazole?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Do not take Zazole by mouth. It is for use only in your vagina.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Zazole is available as a cream or vaginal suppository. Each form comes with an applicator for measuring and inserting the vaginal medicine. The cream is also available in prefilled applicators that each contain one daily dose of terconazole. You may insert the vaginal suppository using your finger if desired.
Wash your hands before and after inserting the cream or suppository.
Zazole is usually applied once daily at bedtime for 3 to 7 days in a row. Follow your doctor's instructions.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antifungal medicine.
Call your doctor if your symptoms do not improve after 3 days, or if you still have symptoms for longer than 7 days. Frequent vaginal yeast infections that do not clear up with treatment may be a sign of a more serious condition.
The single-use cream applicator is for one use only. Throw the applicator away after one use, even if there is still some medicine left in it after inserting your dose.
Your sexual partner should contact a doctor if he develops redness, itching, or other discomfort of the penis. These may be signs that you have passed a yeast infection to your partner.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
An overdose of Zazole is unlikely to occur.
What should I avoid while using terconazole vaginal?
Avoid having sexual intercourse during treatment, unless your doctor says that you may.
Do not use a tampon, vaginal douche, or other vaginal products while you are using Zazole.
Avoid wearing tight-fitting, synthetic clothing such as nylon underwear or panty hose that does not allow air circulation. Wear loose-fitting clothing made of cotton and other natural fibers until your infection is healed.
Zazole side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
new or worsening symptoms;
fever, chills, flu symptoms;
severe vaginal irritation; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
vaginal pain, burning, or itching;
stomach pain; or
increased menstrual cramps.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Zazole?
It is not likely that other drugs you take orally or inject will have an effect on terconazole used in the vagina. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
More about Zazole (terconazole topical)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- En Español
- Drug class: vaginal anti-infectives
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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