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Xermelo

Generic name: telotristat ethyl (tel OH tri stat ETH il)
Brand name: Xermelo
Drug class: Miscellaneous GI agents

Medically reviewed by Drugs.com on Jun 10, 2021. Written by Cerner Multum.

What is Xermelo?

Xermelo is used in adults to treat carcinoid syndrome diarrhea, in combination with another medicine such as octreotide (Sandostatin).

Xermelo may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

Not approved for use by anyone younger than 18 years old.

How should I take Xermelo?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Xermelo is usually taken 3 times per day with food.

Xermelo comes in a monthly case that contains 4 weekly boxes; 1 box of 7 daily doses for use each week. Keep each tablet in the package until you are ready to take a dose.

Octreotide is usually given at least 30 minutes after taking Xermelo.

Xermelo is only part of a complete treatment program that may also include other medications. Do not change your doses or medication schedule without your doctor's advice.

Store at room temperature away from moisture and heat.

Do not share Xermelo with another person, even if they have the same symptoms you have.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Xermelo?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Xermelo side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Xermelo and call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xermelo?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect Xermelo, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Does Xermelo interact with my other drugs?

Enter other medications to view a detailed report.

Frequently asked questions

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.