Generic Name: telotristat ethyl (tel OH tri stat ETH il)
Brand Name: Xermelo
What is Xermelo?
Xermelo works by blocking the production of serotonin in the body. In people who have carcinoid syndrome, serotonin is over-produced and causes symptoms of diarrhea or frequent bowel movements, stomach pain, and flushing (warmth, redness, or tingly feeling).
Xermelo is used to treat carcinoid syndrome diarrhea.
Xermelo may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Xermelo if you are allergic to it.
It is not known whether Xermelo will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether telotristat ethyl passes into breast milk or if it could cause side effects (constipation or stomach discomfort) in the nursing baby. Tell your doctor if you are breast-feeding.
Xermelo is not approved for use by anyone younger than 18 years old.
How should I take Xermelo?
Xermelo is usually taken 3 times per day. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Take with food.
Xermelo comes in a monthly case that contains 4 weekly boxes; 1 box of 7 daily doses for use each week. Keep each tablet in the original package until you are ready to take a dose.
Xermelo is only part of a complete treatment program that may also include other medications. Follow your doctor's instructions very closely.
Store at room temperature away from moisture and heat.
Do not share this medicine with another person, even if they have the same symptoms you have.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Xermelo?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Xermelo side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using Xermelo and call your doctor at once if you have:
severe constipation; or
severe or worsening stomach pain.
Common side effects may include:
nausea, loss of appetite;
headache, depressed mood;
swelling in your hands or feet;
abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Xermelo?
Tell your doctor about all your current medicines and any you start or stop using, including prescription and over-the-counter medicines, vitamins, and herbal products. Xermelo can make other medications less effective. Your doctor may need to adjust your doses of certain other medicines.
Do not change your doses or medication schedule without your doctor's advice.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.01.
More about Xermelo (telotristat)
- Xermelo Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous GI agents