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Xermelo Dosage

Medically reviewed by Last updated on Feb 16, 2021.

Generic name: telotristat ethyl 250mg
Dosage form: tablet

The recommended dosage of Xermelo in adult patients is 250 mg three times daily for patients whose diarrhea is inadequately controlled by SSA therapy.


  • Take Xermelo with food [see Clinical Pharmacology (12.3), Clinical Studies (14)].
  • When short-acting octreotide is used in combination with Xermelo, administer short-acting octreotide at least 30 minutes after administering Xermelo [see Clinical Pharmacology (12.3), Clinical Studies (14)].
  • If a dose is missed, take the next dose at the regular time. Do not take 2 doses at the same time to make up for a missed dose.
  • Discontinue Xermelo if severe constipation develops [see Warnings and Precautions (5.1)].

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.