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Vumon

Generic Name: teniposide (ten IP oh side)
Brand Name: Vumon

Medically reviewed on August 6, 2018

What is Vumon?

Vumon is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Vumon is used to treat acute lymphoblastic leukemia (a type of blood cancer) in children.

Vumon is usually given after other cancer medications have been tried without successful treatment.

Vumon may also be used for purposes not listed in this medication guide.

Important Information

Do not receive Vumon if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are receiving this medicine, whether you are a man or a woman. This medicine use by either parent may cause birth defects.

Before receiving Vumon, tell your doctor if you have kidney or liver disease, Down syndrome, bone marrow suppression, low albumin levels, or a weak immune system.

Vumon can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection.

Using Vumon may increase your risk of developing other types of cancer, such as leukemia. Talk with your doctor about your specific risk.

Call your doctor at once if you have a serious side effect such as fever, chills, flu symptoms, mouth sores, easy bruising, unusual bleeding, pale skin, fast heart rate, trouble breathing, severe headache, severe nausea and vomiting, or feeling like you might pass out.

Before taking this medicine

You should not receive this medication if you are allergic to Vumon or to a medication ingredient called Cremophor (synthetic castor oil).

To make sure you can safely receive Vumon, tell your doctor if you have any of these other conditions:

  • Down Syndrome;

  • bone marrow suppression;

  • liver or kidney disease;

  • low albumin levels; or

  • a weak immune system (from disease or from taking certain medicines).

Do not receive Vumon if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are receiving this medicine, whether you are a man or a woman. This medicine use by either parent may cause birth defects.

This medication can decrease sperm count and may affect fertility in men (your ability to have children).

It is not known whether teniposide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using teniposide.

Using Vumon may increase your risk of developing other types of leukemia. Talk with your doctor about your specific risk.

How should I use teniposide?

Vumon is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. The medicine is sometimes given slowly through an IV infusion, and can take up to 60 minutes to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Vumon is injected.

Vumon can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water right away.

You will be watched closely for at least 60 minutes after the start of your Vumon infusion, to make sure you do not have an allergic reaction to the medication.

Vumon can lower blood cells that help your body fight infections. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Vumon.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while receiving Vumon?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Vumon can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Vumon side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fever, chills, itching, body aches, flu symptoms, sores in your mouth and throat;

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

  • fast or pounding heartbeats, wheezing, chest tightness, trouble breathing;

  • severe headache, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats;

  • pain, burning, irritation, or skin changes where the injection was given;

  • feeling like you might pass out; or

  • severe nausea and vomiting.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Vumon?

Tell your doctor about all other medicines you use, especially drugs that weaken the immune system, such as:

  • cancer medicine;

  • steroids; or

  • medicines to prevent rejection of a transplanted organ.

This list is not complete and other drugs may interact with Vumon. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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