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Teniposide Pregnancy and Breastfeeding Warnings

Teniposide is also known as: Vumon

Teniposide Pregnancy Warnings

Use should be avoided.

US FDA pregnancy category: D

-This drug can harm a developing fetus.
-Adequate methods of contraception should be encouraged.
-If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.
-In animal studies, this drug caused a decrease in sperm count and genetic damage to sperm. Men of reproductive age should be advised of the possibility that this drug may compromise their ability to father a child and that there is some possibility for birth defects if they do. They should be counseled on the possibility of storing sperm for future artificial insemination.

Animal studies have revealed evidence of embryotoxicity and teratogenicity. Major anomalies included spinal and rib defects, deformed extremities, anophthalmia, and celosomia. There are no controlled data in human pregnancy.

US FDA pregnancy category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Teniposide Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

-The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Teniposide (teniposide)." WG Critical Care (2019):

References for breastfeeding information

  1. "Product Information. Teniposide (teniposide)." WG Critical Care (2019):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.