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Generic Name: baclofen (BAK loe fen)
Brand Name: Lioresal
Medically reviewed on August 10, 2018
What is Lioresal?
Lioresal is a muscle relaxer and an antispastic agent.
Lioresal is used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness.
Lioresal is sometimes used to treat muscle spasms and other symptoms in people with injury or disease of the spinal cord.
Lioresal may also be used for purposes not listed in this medication guide.
Do not use Lioresal at a time when you need muscle tone for safe balance and movement during certain activities.
Do not stop using Lioresal suddenly, or you could have unpleasant withdrawal symptoms.
Before taking this medicine
You should not use Lioresal if you are allergic to it.
To make sure Lioresal is safe for you, tell your doctor if you have:
epilepsy or other seizure disorder;
a history of stroke or blood clots; or
if you also use a narcotic (opioid) medication.
Using Lioresal during pregnancy could harm the unborn baby. In animal studies, this medicine caused low birth weight and birth defects. However, it is not known whether these effects would occur in humans. Tell your doctor if you are pregnant or if you become pregnant while using Lioresal.
It is not known whether baclofen passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using baclofen.
Using Lioresal may increase your risk of developing an ovarian cyst. Talk with your doctor about your specific risk.
Lioresal is not approved for use by anyone younger than 12 years old.
How should I take Lioresal?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Call your doctor if your muscle symptoms do not improve, or if they get worse.
Do not stop using Lioresal suddenly, or you could have unpleasant withdrawal symptoms such as hallucinations or a seizure. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include muscle weakness, vomiting, drowsiness, dilated or pinpoint pupils, weak or shallow breathing, seizure, or coma.
What should I avoid while taking Lioresal?
Do not use Lioresal at a time when you need muscle tone for safe balance and movement during certain activities. In some situations, it may be dangerous for you to have reduced muscle tone.
Drinking alcohol with Lioresal can cause side effects.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Lioresal side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
weak or shallow breathing;
confusion, hallucinations; or
a seizure (convulsions).
Common side effects may include:
drowsiness, dizziness, weakness, tired feeling;
sleep problems (insomnia);
urinating more often than usual.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Lioresal?
Taking Lioresal with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Other drugs may interact with baclofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 6.01.
More about Lioresal (baclofen)
- Lioresal Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- 19 Reviews
- Generic Availability
- Drug class: skeletal muscle relaxants
- Lioresal (Advanced Reading)
- Lioresal Double Strength (Advanced Reading)
- Lioresal Intrathecal (Advanced Reading)
Other brands: Gablofen