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Generic name: cefiderocol SEF-i-DER-oh-kol ]
Drug class: Other cephalosporins

Medically reviewed by on Oct 23, 2023. Written by Cerner Multum.

What is Fetroja?

Fetroja is a cephalosporin (SEF-a-lo-SPOR-in) antibiotic that is used to treat serious bladder or kidney infections in adults.

Fetroja is also used to treat adults who have developed pneumonia while being in a hospital or using a ventilator.

Fetroja may also be used for purposes not listed in this medication guide.

Fetroja side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Fetroja may cause serious side effects. Call your doctor at once if you have:

Common side effects of Fetroja may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Fetroja can cause serious or life-threatening allergic reactions. Tell your doctor if you have an allergy to an antibiotic, especially penicillin.

Before taking this medicine

Fetroja can cause serious or life-threatening allergic reactions. You should not use Fetroja if you have ever had a severe allergic reaction to an antibiotic, such as:

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

How is Fetroja given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Fetroja is injected into a vein.

This medicine must be given slowly over 3 hours.

Ask your doctor or pharmacist if you don't understand how to use an injection.

Fetroja must be mixed with a liquid (diluent) and then further diluted with another liquid in an IV bag. Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine has changed colors or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Fetroja is usually given for 7 to 14 days.

Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Fetroja will not treat a viral infection (flu or a common cold).

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Fetroja.

Store vials in the original carton in a refrigerator. Protect from light.

After mixing a diluent into the vial: Store at room temperature and further dilute into an IV bag within 1 hour.

After diluting the mixture in an IV bag: Store the bag at room temperature for up to 6 hours, or in a refrigerator for up to 24 hours. Protect from light.

After removing the IV bag from a refrigerator, you must use the medicine within 6 hours once it reaches room temperature.

Each IV bag is for one use only. Throw it away after one use, even if there is still medicine left inside.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Fetroja?

Antibiotic medicines can cause diarrhea. Tell your doctor if you have diarrhea that is watery or bloody.

What other drugs will affect Fetroja?

Other drugs may affect Fetroja, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.