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Diovan HCT

Generic Name: hydrochlorothiazide and valsartan (HYE droe klor oh THYE a zide and val SAR tan)
Brand Name: Diovan HCT

Medically reviewed on July 18, 2017

What is Diovan HCT?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Valsartan is an angiotensin II receptor antagonist. Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Diovan HCT is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Diovan HCT is usually given after other blood pressure medicines have been tried without success.

Diovan HCT may also be used for purposes not listed in this medication guide.

Important Information

Do not use if you are pregnant. If you become pregnant, stop taking Diovan HCT and tell your doctor right away.

If you have diabetes, do not use Diovan HCT together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

Before taking this medicine

You should not use this medicine if you are allergic to amlodipine (Norvasc) or valsartan (Diovan), or if:

  • you are unable to urinate; or

  • you are allergic to sulfa drugs.

If you have diabetes, do not use Diovan HCT together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

You may also need to avoid taking Diovan HCT with aliskiren if you have kidney disease.

To make sure Diovan HCT is safe for you, tell your doctor if you have ever had:

  • an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood);

  • a heart attack;

  • angina (chest pain), congestive heart failure;

  • kidney disease;

  • liver disease;

  • gallstones;

  • an allergy to penicillin;

  • a severe allergic reaction to another heart or blood pressure medicine;

  • lupus, gout, or high levels of uric acid in your blood;

  • glaucoma; or

  • if you are on a low-salt diet.

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Diovan HCT can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Hydrochlorothiazide and valsartan can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Diovan HCT is not approved for use by anyone younger than 18 years old.

How should I take Diovan HCT?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use Diovan HCT in larger or smaller amounts or for longer than recommended.

You may take this medication with or without food.

Your blood pressure will need to be checked often. Your kidney function may also need to be checked.

You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual.

If you need surgery, tell the surgeon ahead of time that you are using Diovan HCT.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Blood pressure medication is only part of a complete treatment program that may also include diet, exercise, regular blood pressure testing, lifestyle changes, and other medications. Follow your doctor's instructions very closely.

Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or stop taking any of your medications without your doctor's advice.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Diovan HCT?

Do not use potassium supplements or salt substitutes while you are taking Diovan HCT, unless your doctor has told you to.

Drinking alcohol can further lower your blood pressure and may cause side effects.

If you also take cholestyramine or colestipol, avoid taking it for at least 4 hours before or 4 hours after you have taken Diovan HCT.

Diovan HCT may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Diovan HCT side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • swelling in your hands or feet, rapid weight gain;

  • eye pain, vision problems;

  • an unusual skin rash;

  • pounding heartbeats or fluttering in your chest;

  • jaundice (yellowing of the skin or eyes); or

  • signs of an electrolyte imbalance--dry mouth, increased thirst, drowsiness, confusion, feeling restless, vomiting, muscle pain or weakness, lack of energy, fast heartbeats, little or no urine, or a seizure.

Common side effects include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Diovan HCT?

Many drugs can interact with Diovan HCT. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete and many other drugs can interact with Diovan HCT. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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