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carbinoxamine

Generic Name: carbinoxamine (car bi NOX a meen)
Brand Name: Arbinoxa, Karbinal ER, Ryvent, ...show all 15 brand names

What is carbinoxamine?

Carbinoxamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Carbinoxamine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Carbinoxamine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about carbinoxamine?

Do not breast-feed a baby while taking this medicine.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not give this medicine to a child younger than 2 years old. Death can occur from the misuse of cough and cold medicines in very young children.

What should I discuss with my healthcare provider before taking carbinoxamine?

You should not use carbinoxamine if you are allergic to it.

Do not use carbinoxamine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Do not breast-feed a baby while taking carbinoxamine. This medicine may cause side effects in the nursing baby.

Do not give this medicine to a child younger than 2 years old. Death can occur from the misuse of cough and cold medicines in very young children. Talk with your doctor about other FDA-approved products available for use in young children with cold or allergy symptoms. Always ask a doctor before giving a cough or cold medicine to a child.

You should not use antihistamine medication to make a child sleepy.

To make sure carbinoxamine is safe for you, tell your doctor if you have:

  • narrow-angle glaucoma;

  • heart disease or high blood pressure;

  • a stomach ulcer;

  • a blockage in your digestive tract (stomach or intestines);

  • a bladder obstruction or other urination problems;

  • an enlarged prostate;

  • asthma; or

  • overactive thyroid.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

How should I take carbinoxamine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

You may need to shake the oral suspension (liquid) before using. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Since carbinoxamine is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of carbinoxamine can be fatal, especially to a child.

Overdose symptoms may include extreme drowsiness or restless feeling, dilated pupils, hallucinations, or seizure (convulsions).

What should I avoid while taking carbinoxamine?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid drinking alcohol. It may increase certain side effects of carbinoxamine.

Ask a doctor or pharmacist before using any other cold, allergy, or sleep medicine. Many combination medicines contain antihistamines. Taking certain products together can cause you to get too much of this type of medicine.

Carbinoxamine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using carbinoxamine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • little or no urination;

  • wheezing, tightness in your chest;

  • pounding heartbeats or fluttering in your chest;

  • easy bruising or bleeding; or

  • pale or yellowed skin, dark colored urine, fever, confusion or weakness.

Side effects such as constipation, dizziness, and confusion may be more likely in older adults.

Common side effects may include:

  • drowsiness, dizziness;

  • loss of coordination;

  • dry mouth or nose;

  • upset stomach; or

  • feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Carbinoxamine dosing information

Usual Adult Dose for Allergic Rhinitis:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet, timed-release (carbinoxamine maleate 8 mg): 1 tablet orally every 12 hours

Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg): 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL): 5 mL orally every 12 hours

Liquid (carbinoxamine maleate 4 mg/5 mL): 5 mL orally 4 times a day

Liquid (carbinoxamine maleate 1.5 mg/5 mL): 10 mL orally 4 times a day

Extended release suspension (carbinoxamine tannate 3.6 mg/5 mL): 10 to 20 mL orally every 12 hours


Liquid (carbinoxamine maleate 1.75 mg/5 mL): 10 mL orally 4 times a day

Usual Adult Dose for Allergic Urticaria:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg): 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL): 5 mL orally every 12 hours

Usual Adult Dose for Allergic Reaction:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Adult Dose for Allergic Conjunctivitis:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Adult Dose for Dermatographism:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Adult Dose for Vasomotor Rhinitis:

Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Pediatric Dose for Allergic Rhinitis:

Liquid (carbinoxamine maleate 1.75 mg/5 mL):
Liquid (carbinoxamine maleate 1.5 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 5 mL orally 4 times a day
>=6 years: 10 mL orally 4 times a day

Liquid (carbinoxamine maleate 4 mg/5 mL):
Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally 4 times a day
>=6 years: 5 mL orally 4 times a day

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet, timed-release (carbinoxamine maleate 8 mg):
6 to 12 years: 1/2 tablet orally every 12 hours
>=12 years: 1 tablet orally every 12 hours

Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg):
>=12 years: 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period

Extended release suspension (carbinoxamine tannate 3.6 mg/5 mL):
2 years to 6 years: 2.5 to 5 mL orally every 12 hours
6 years to 12 years: 5 to 10 mL orally every 12 hours
12 years to 18 years: 10 to 20 mL orally every 12 hours

Usual Pediatric Dose for Allergic Urticaria:

Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally every 12 hours
>=6 years: 5 mL orally every 12 hours

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg):
>=12 years: 1 capsule orally every 12 hours, not to exceed 2 capsules per day

Usual Pediatric Dose for Allergic Reaction:

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Pediatric Dose for Allergic Conjunctivitis:

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Pediatric Dose for Dermatographism:

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Usual Pediatric Dose for Vasomotor Rhinitis:

Solution (carbinoxamine maleate 4 mg/5 mL):
<2 years: Safety and effectiveness unknown
2 years to 6 years: 2.5 mL orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

Tablet (carbinoxamine maleate 4 mg):
<2 years: Safety and effectiveness unknown
2 to 6 years: 1/2 tablet orally daily as needed; may increase dosage as needed, approximately 0.2 to 0.4 mg/kg/day in divided doses every 6 to 8 hours
>=6 years: 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours

What other drugs will affect carbinoxamine?

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking carbinoxamine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

See also: Side effects (in more detail)

Where can I get more information?

  • Your pharmacist can provide more information about carbinoxamine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 8.01.

Date modified: August 01, 2017
Last reviewed: April 03, 2017

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