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Karbinal ER

Generic Name: carbinoxamine (car bi NOX a meen)
Brand Name: Arbinoxa, Karbinal ER, Ryvent

Medically reviewed: April 3, 2017

What is Karbinal ER?

Karbinal ER is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Karbinal ER is used to treat runny or stuffy nose, sneezing, itching, watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Karbinal ER may also be used for purposes not listed in this medication guide.

Important Information

Do not breast-feed a baby while taking this medicine.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not give this medicine to a child younger than 2 years old. Death can occur from the misuse of cough and cold medicines in very young children.

Before taking this medicine

You should not use Karbinal ER if you are allergic to it.

Do not use Karbinal ER if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Do not breast-feed a baby while taking Karbinal ER. This medicine may cause side effects in the nursing baby.

Do not give this medicine to a child younger than 2 years old. Death can occur from the misuse of cough and cold medicines in very young children. Talk with your doctor about other FDA-approved products available for use in young children with cold or allergy symptoms. Always ask a doctor before giving a cough or cold medicine to a child.

You should not use antihistamine medication to make a child sleepy.

To make sure Karbinal ER is safe for you, tell your doctor if you have:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

How should I take Karbinal ER?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

You may need to shake the oral suspension (liquid) before using. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Since Karbinal ER is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Karbinal ER can be fatal, especially to a child.

Overdose symptoms may include extreme drowsiness or restless feeling, dilated pupils, hallucinations, or seizure (convulsions).

What should I avoid while taking Karbinal ER?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid drinking alcohol. It may increase certain side effects of Karbinal ER.

Ask a doctor or pharmacist before using any other cold, allergy, or sleep medicine. Many combination medicines contain antihistamines. Taking certain products together can cause you to get too much of this type of medicine.

Karbinal ER side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Karbinal ER and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • little or no urination;

  • wheezing, tightness in your chest;

  • pounding heartbeats or fluttering in your chest;

  • easy bruising or bleeding; or

  • pale or yellowed skin, dark colored urine, fever, confusion or weakness.

Side effects such as constipation, dizziness, and confusion may be more likely in older adults.

Common side effects may include:

  • drowsiness, dizziness;

  • loss of coordination;

  • dry mouth or nose;

  • upset stomach; or

  • feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Karbinal ER?

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking Karbinal ER with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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