How is Zulresso administered for the treatment of Postpartum Depression?
How long does the treatment take? Can I receive the injection at home?
Zulresso is an injection that is given as a continuous intravenous (IV) infusion into your vein over a period of 60 hours (2.5 days).
Zulresso (brexanolone) is the first drug to be FDA approved specifically for postpartum depression, a major depressive episode that occurs following childbirth. Severe cases of postpartum depression can be life life-threatening.
Zulresso can cause serious side effects including excessive sedation (sleepiness) or sudden loss of consciousness. Before you receive Zulresso, you must first be enrolled in a program called the Zulresso REMS, a restricted program that requires that the treatment is provided under medical supervision in a certified health care facility.
You will need to be hospitalized for the entire duration of treatment, so you cannot receive the injection at home. During this period, you will be monitored for excessive sedation every two hours during the normal time you are awake, and you will have continuous pulse oximetry monitoring to monitor oxygen levels in your blood. You will also need to be accompanied during all interactions with your child(ren). Once the treatment is complete, you should not drive, operate machinery, or do other dangerous activities until feelings of sleepiness have completely gone away.
Read next
How to sleep while taking Cymbalta?
Not being able to sleep (also called insomnia) is one of the most common side effects reported by people taking Cymbalta. In some people, this side effect improves after a couple of weeks of taking Cymbalta, but difficulty falling asleep or staying asleep can persist in others. Here are some ways you can improve sleep while taking Cymbalta:
- Take your dose of Cymbalta in the morning. Cymbalta may be given once a day or twice a day but for those people experiencing insomnia, it should be taken just once a day in the morning
- Swallow Cymbalta capsules whole; do not crush, chew, or open up the capsules and sprinkle them on food because this may cause Cymbalta to be absorbed more quickly than intended, increasing the risk of side effects such as insomnia...
What is Exxua?
Exxua (gepirone hydrochloride) is new antidepressant that was FDA approved on September 22, 2023 for major depressive disorder (MDD). Exxua works slightly differently to other currently available antidepressants which may improve its side effect profile, particularly with regards to having less of an impact on sexual functioning and negligible weight gain. Continue reading
Can depression cause headaches?
Yes, headaches can be a symptom of depression, among many other symptoms such as feeling sad, tearful and loss of interest in everyday activities. An association with depression has also been identified in patients with migraine headaches. Severe headaches may also cause a person to feel depressed. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Rexulti
Rexulti (brexpiprazole) is a prescription antipsychotic medication used in the treatment of major ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Vyepti
Vyepti (eptinezumab-jjmr) is used for the preventive treatment of migraine. Includes Vyepti ...
Depakote
Depakote is used to treat various types of seizure disorders. Learn about side effects ...
Topamax
Topamax (topiramate) is used to prevent seizures in adults and children and to prevent migraine ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Inderal
Inderal (propranolol) is used to treat angina, high blood pressure and heart rhythm disorders ...
Related medical questions
- SSRIs vs SNRIs - What's the difference between them?
- How long do venlafaxine withdrawal symptoms last?
- How long does Xanax last for / stay in your system?
- Klonopin vs Xanax - How are they different?
- Can I stop taking Wellbutrin suddenly or should I taper off?
- Why does Lexapro cause weight gain?
- How long does Zoloft (sertraline) take to work?
- Lorazepam vs Xanax: What is the difference?
- When is the best time to take Lexapro?
- Lexapro vs Zoloft: How do they compare?
- How long for an increased dose of Zoloft to work?
- How long does it take for Lexapro to work?
- Why should you take aripiprazole in the morning?
- Does Abilify cause weight gain?
- What is bromazepam used for?
- Does Adderall help with anxiety and depression?
- How long does it take for Cymbalta to work?
- Prozac vs Zoloft - What are the Differences & Similarities?
- How long do Abilify withdrawal symptoms last?
- Modafinil: Smart Drug For Decision Fatigue Or Workaholic Crutch?
- What antidepressants are usually taken with Abilify?
- What do Cymbalta brain zaps feel like?
- Prozac vs Xanax: How do they compare?
- Does Lexapro cause night sweats?
- Vraylar vs Abilify - How do they compare?
- Does Remeron help with sleep?
- What is agomelatine used for?
Drug information
Related support groups
- Brexanolone (1 questions, 3 members)
- Zulresso (1 questions, 3 members)
- Depression (2,241 questions, 8,784 members)
- Postpartum Depression (44 questions, 109 members)