Can you take paracetamol (acetaminophen) with antibiotics?
Medically reviewed by Drugs.com. Last updated on March 31, 2025.
There are literally hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take paracetamol (acetaminophen) at the same time that you take the antibiotic.
The best way to determine if you can take any two medications together is to have a drug interaction screen performed by a health care provider.
For example, antibiotics that may affect your liver could interact with paracetamol (acetaminophen), which can also be toxic to the liver in excessive doses or when combined with alcohol.
Usually this is not a problem, but you should always check.
See also: Drug Interaction Checker
Read next
Can you take tramadol with acetaminophen, ibuprofen, or aspirin?
Yes, it is safe for most people to take tramadol with acetaminophen, ibuprofen, or aspirin if they are old enough (aspirin is not recommended for children less than 16 years and tramadol should not be taken by children under the age of 12). Continue reading
Acetaminophen vs paracetamol: What do you need to know?
Acetaminophen (Tylenol) found in the U.S is the same medicine as paracetamol (Panadol) used throughout many regions of the world, including Europe, Australia, India and New Zealand. Acetaminophen and paracetamol are the generic names of medicines used to treat mild pain, headache and fever. Continue reading
Advil (ibuprofen) & Tylenol (acetaminophen) together, safe?
Yes, it is safe to take ibuprofen (Advil) and acetaminophen (Tylenol) together if you need to for extra pain relief, such as for a dental extraction. Taking ibuprofen and acetaminophen together works better to relieve pain than taking ibuprofen and acetaminophen separately. This is because they work in different ways with few side effects. Continue reading
See also:
Related medical questions
- What's the best medicine for sore throat?
- What is paracetamol / Panadol called in the US?
- Acetaminophen vs Ibuprofen: Which is better?
- What medications cause liver enzymes to be elevated?
- What temperature is considered a fever?
- Is it safe to take acetaminophen every day?
- What cold medicine can you take with diabetes?
- How long does Percocet stay in your system?
- Does Mucinex help with Covid?
- Is Tylenol (acetaminophen) a blood thinner?
- Which painkiller should you use?
- Is acetaminophen (Tylenol) an NSAID Drug?
- Can I take Tylenol while pregnant?
- Cold, flu, hay fever, or COVID - Which one do I have?
- Can you Double up on Pain Medications? Safe Painkiller Combinations
- How long does it take for Tylenol to start working?
- Is acetaminophen the same as Tylenol?
- Can I give my dog or cat Tylenol (acetaminophen)?
- OTC Water Pills
- What do I need to know about Drug Interactions?
- Is Tylenol (acetaminophen) an anti-inflammatory drug?
- Over the Counter Medication for Pets
- How do I treat back pain without using opioids?
- How Can I Treat Muscle Strain or Pain?
- What antibiotics are used to treat bronchitis?
- How do I treat a mild case of COVID-19 at home?
- What Vaccines do I need if I'm over 50?
Drug information
Related support groups
- Acetaminophen (162 questions, 218 members)
- Paracetamol (38 questions, 73 members)