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How is Livalo different from other statins?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Oct 14, 2020.

Is Livalo a good statin?

Official Answer

by Drugs.com

Livalo produces a larger increase in high-density lipoprotein-cholesterol (HDL-C) levels when compared to some of the other statins. This increase in HDL-C levels is sustained over the long-term.

HDL-Cholesterol is often referred to as the “good” cholesterol as it collects any excess cholesterol and takes it back to the liver, where it is broken down and then removed from the body. Increasing your HDL cholesterol can lower your risk of heart disease and stroke.

Livalo reduces levels of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG) to a similar level as the most potent statins, simvastatin and atorvastatin.

Livalo has less drug-drug interaction than atorvastatin and simvastatin, as Livalo is minimally metabolized by cytochrome P450 (CYP) enzyme. Pravastatin and fluvastatin have the lowest risk of drug interactions as they are not metabolized by cytochrome p450 3A4 at all.

Bottom line:

  • Livalo is very effective at increasing high-density lipoprotein-cholesterol (HDL-C) levels.
  • Livalo is very effective at decreasing levels of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG).
  • Livalo has less drug-drug interaction than atorvastatin and simvastatin.
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