How does Taltz work?
The active ingredient in Taltz, ixekizumab, is a monoclonal antibody that works by inhibiting the inflammatory response in adults with plaque psoriasis, active psoriatic arthritis, active ankylosing spondylitis, and non-radiographic axial spondyloarthritis.
Taltz selectively binds with interleukin 17A (IL-17A) cytokine, a naturally occurring substance that can cause inflammation. Taltz inhibits the release of pro-inflammatory cytokines and chemokines by inhibiting the interaction of IL-17A with the IL-17 receptor.
Taltz affects the immune system. It may increase the risk of infections, which can be serious. Taltz should not be used in patients who have any symptoms of infection, unless a doctor advises otherwise.
Read next
What are IL-17 Inhibitors and how do they work?
IL-17 inhibitors are biologic drugs that block interleukin-17, a key protein that fuels inflammation in autoimmune diseases.
Continue reading
How long before Taltz works?
Treatment with Taltz (ixekizumab) starts to improve symptoms in patients with moderate-to-severe psoriasis within about 1-2 weeks, according to clinical trial results. After 12 weeks, nearly 90% of patients will have significantly clearer skin. Continue reading
Can I drink alcohol with Taltz?
Alcohol is not known to interact with Taltz (ixekizumab), a humanized interleukin-17A antagonist used to treat adults and children with moderate-to-severe plaque psoriasis and other conditions.
While Taltz may not interact with alcohol, the American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) recommend that dermatologists strongly advise patients with psoriasis to limit alcohol intake. It is thought that consumption of alcohol increases the risk for severe disease in patients with psoriasis. Continue reading
See also:
Related medical questions
- Is weight gain a side effect of Taltz?
- What are the new drugs for plaque psoriasis?
- What are Monoclonal Antibodies and how do they work?
- What are 6 key Taltz side effects to watch out for?
- How does Taltz compare to Cosentyx for psoriatic arthritis?
- What causes Plaque Psoriasis?
- How do you use the Taltz Autoinjector?
Drug information
Related support groups
- Ixekizumab (6 questions, 4 members)
- Taltz (11 questions, 16 members)