How does Evista (raloxifene) work?
Evista (raloxifene) is not a hormone, it mimics the action of estrogen on bones while at the same time blocking the effect of estrogen on other tissues. It is known as an estrogen agonist/antagonist (formerly called a selective estrogen receptor modulator [SERM]) and this action decreases bone loss in postmenopausal women.
Using Evista long-term does not carry the same risk of cancer in breast and womb tissue that has been associated with estrogen-based hormone therapies. However, Evista can increase the risk of deep vein thrombosis and stroke and may increase the incidence of hot flushes and leg cramps. Evista may also be used to treat osteoporosis in postmenopausal women with invasive breast cancer. But evidence suggests it may not be as effective as bisphosphonates or estrogen at preventing bone loss.
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How does teriparatide (Forteo) work?
Teriparatide (Forteo), is a synthetic form of parathyroid hormone - a hormone produced naturally by the body which helps maintain blood levels of calcium within a very tight range; which in turn controls calcium levels within bone - determining how strong and dense the bones are. Continue reading
What's the difference between Prolia and Reclast?
Prolia (denosumab) and Reclast (zoledronic acid) are injections that can be used to treat or prevent osteoporosis. But they each work differently because Prolia is a monoclonal antibody (it may also be called a miscellaneous bone resorption agent) and Reclast is a bisphosphonate which means they have different side effects, other uses, tolerability, and effectiveness profiles. Both are prescription medicines. One of the main problems with Prolia is safely stopping it. Continue reading
How do you give a Prolia injection?
Prolia is a prescription medicine injected under the skin (called a subcutaneous injection) and is given once every 6 months. You do not give Prolia to yourself. You will receive your Prolia injection from your healthcare provider at a their office or clinic. Continue reading
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