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What is Doptelet used for and how does it work?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Aug 1, 2025.

Official Answer by Drugs.com

How long does it take for Doptelet to work?

Doptelet (avatrombopag) is used to treat low platelet levels (thrombocytopenia) in:

Low platelet levels risk

How does Doptelet work?

Platelet production in the body starts with hematopoietic stem cells (HSCs), which develop into megakaryocyte cells that make platelets.

Doptelet works by increasing the number of hematopoietic stem cells, which leads to the production of more megakaryocytes and, in turn, raises platelet levels.

Doptelet's mechanism of action is as a thrombopoietin receptor agonist, one of the platelet-stimulating agents.

How long does Doptelet take to work?

Bottom line:

References

Doptelet Prescription Information: https://www.drugs.com/pro/doptelet.html

Avatrombopag for the treatment of immune thrombocytopenia and thrombocytopenia of chronic liver disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733339/

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