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How do you take Doptelet before a medical or dental procedure?

Medically reviewed by Last updated on June 17, 2021.

Official Answer


Doptelet is taken by mouth (with food) once a day for 5 days in a row as directed by your doctor. Doptelet treatment should be started 10 to 13 days before the scheduled medical or dental procedure.

Doptelet (avatrombopag) is an oral thrombopoietin receptor agonist (TPO-RA) used for thrombocytopenia (low blood platelet counts) in patients with chronic liver disease scheduled for a medical or dental procedure.

People with chronic liver disease who have low platelet counts have increased risk of bleeding. Doptelet works to safely increase the platelet count and prevent excessive bleeding during the procedure.

Your doctor will prescribe your specific dose of Doptelet based on your platelet count before your procedure. You will then have your procedure 5 to 8 days after your last dose of Doptelet.

Doptelet is NOT used to normalize platelet counts in adults with chronic liver disease.

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