What is the difference between Tiglutik and Rilutek?
Medically reviewed by Drugs.com. Last updated on Oct 15, 2018.
Official Answerby Drugs.com
Tiglutik is an oral suspension (liquid) and Rilutek is a tablet.
- Tiglutik is an easy-to-swallow, thickened, oral suspension of riluzole given twice daily via the supplied oral syringe. The thickened formula may be easier for some ALS patients to swallow.
- Rilutek comes as an oral 50 mg, film-coated tablet.
- Both drugs should be taken twice a day at least one hour before or two hours after a meal.
Riluzole works by decreasing levels of glutamate, an amino acid in the body that affects nerves that send messages from the brain to muscles. People with amyotrophic lateral sclerosis may have high levels of glutamate, which can damage these nerve cells leading to loss of motor control.