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What is the difference between Admelog and Humalog?

Medically reviewed by Drugs.com. Last updated on Jan 2, 2025.

Official Answer by Drugs.com

Admelog is highly similar to Humalog in it's safety, effectiveness, and dosing. As a follow-on insulin, Admelog will provide a more affordable option to Humalog

Both Admelog and Humalog are insulin lispro injections used to control blood sugar (glucose) in patients 3 years and older with type 1 diabetes and adults with type 2 diabetes. Humalog, from Eli Lilly, is the original reference product and Admelog, from Sanofi, is the first rapid-acting, mealtime insulin approved as a “follow-on” product that relied, in part, on the FDA’s finding of safety and effectiveness for Humalog to support approval (approved via 505(b)(2), an abbreviated pathway).

How does Admelog come?

Admelog (insulin lispro injection) is available in the U.S. as a 100 Unit/mL (U-100) multidose 10 mL vial and as the disposable, 3 mL SoloStar prefilled pen. Admelog can be administered by injection under the skin (subcutaneously), by continuous subcutaneous infusion (by pump), or by intravenous (IV) infusion after dilution. Admelog is used within 15 minutes before a meal or immediately after.

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Does Humalog need to be refrigerated?

Humalog (insulin lispro) should be stored in a refrigerator (36° to 46°F [2° to 8°C]) until it is opened, but do not freeze it. Once your Humalog vial, cartridge or prefilled pen is in use, it can be stored at room temperature, below 86°F (30°C), for 28 days. Discard it after 28 days. Continue reading

How long does it take for Humalog to work?

In general, Humalog starts to work about 15 minutes after it is injected, and peak effects happen after an hour or two. Humalog's effects usually last 2-4 hours. Continue reading

What type of insulin is Humalog?

Humalog (insulin lispro) is a fast-acting insulin. It begins working to lower blood sugar levels about 15 minutes after injection, reaches a peak in about 1 hour, and continues to work for 2 to 4 hours. Humalog helps to control the blood sugar spikes that may occur during mealtime. It is used within 15 minutes before eating or right after eating a meal. Continue reading

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