Drug Interaction Report

Talk to your doctor before using doxylamine together with galantamine. Medications like doxylamine may reduce the effectiveness of galantamine. In addition, patients with Alzheimer's disease or other dementia may be more likely to experience nervous system side effects of doxylamine such as drowsiness, confusion, and mental impairment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with doxylamine. Do not use more than the recommended dose of doxylamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Galantamine should be taken with food, and you should drink plenty of fluids throughout the day to reduce the severity of certain side effects such as nausea, vomiting, diarrhea, loss of appetite, and/or weight loss. Extended-release formulations should be swallowed whole (i.E., do not crush, chew, or divide the pill) and are often recommended to be taken in the morning. You should speak with your healthcare provider before using grapefruit products (fruit, juice, supplements) with galantamine as they may increase the blood levels and side effects of galantamine. You should also contact your healthcare provider if you experience changes in your heart rate, seizures, difficulty breathing, trouble urinating, dizziness, fainting, nausea, vomiting, diarrhea, and/or unexpected weight loss. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.