Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- desipramine
- dyphylline / ephedrine / guaifenesin / phenobarbital
Interactions between your drugs
desipramine ePHEDrine
Applies to: desipramine, dyphylline / ephedrine / guaifenesin / phenobarbital
Desipramine should not be used with ePHEDrine except in cases of emergency. If your doctor wants you to take this combination a dosage adjustment may be necessary. Your blood pressure may need to be checked more frequently. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
desipramine PHENobarbital
Applies to: desipramine, dyphylline / ephedrine / guaifenesin / phenobarbital
Using desipramine together with PHENobarbital can cause either medication to be less effective. This could be especially dangerous if you are using PHENobarbital to prevent seizures. Talk to your doctor before using these medications together. You may need a dose adjustment or special tests to safely take these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ePHEDrine dyphylline
Applies to: dyphylline / ephedrine / guaifenesin / phenobarbital, dyphylline / ephedrine / guaifenesin / phenobarbital
Information for this minor interaction is available on the professional version.
Drug and food interactions
PHENobarbital food
Applies to: dyphylline / ephedrine / guaifenesin / phenobarbital
Ask your doctor before using PHENobarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of PHENobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with PHENobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
desipramine food
Applies to: desipramine
Ask your doctor before using desipramine together with ethanol (alcohol), this can alter the effects of desipramine and cause increased side effects. Call the doctor if you experience uneven heartbeats, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, feeling light-headed, and seizures. You should be warned not to exceed recommended dosages, to avoid alcohol, and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ePHEDrine food
Applies to: dyphylline / ephedrine / guaifenesin / phenobarbital
Both ePHEDrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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