Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Biaxin XL (clarithromycin)
- ramelteon
Interactions between your drugs
clarithromycin ramelteon
Applies to: Biaxin XL (clarithromycin), ramelteon
Clarithromycin may increase the blood levels and effects of ramelteon. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience excessive drowsiness or increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
ramelteon food
Applies to: ramelteon
Taking ramelteon with a high-fat or heavy meal may delay the onset of sleep. For faster sleep onset, ramelteon should not be administered with or immediately after a high-fat or heavy meal. This will make it easier for your body to absorb the medication. Do not drink alcohol while you are taking ramelteon. It can increase some of the side effects including dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.
clarithromycin food
Applies to: Biaxin XL (clarithromycin)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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