Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- methenamine / sodium salicylate
- Pepto-Bismol (bismuth subsalicylate)
Interactions between your drugs
sodium salicylate bismuth subsalicylate
Applies to: methenamine / sodium salicylate, Pepto-Bismol (bismuth subsalicylate)
Using sodium salicylate together with bismuth subsalicylate is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, pain, bleeding, and ulceration. Bruising and other bleeding complications may also occur. You should take these medications with food to lessen gastrointestinal side effects. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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