Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Azopt (brinzolamide ophthalmic)
- Neptazane (methazolamide)
Interactions between your drugs
methazolAMIDE brinzolamide ophthalmic
Applies to: Neptazane (methazolamide), Azopt (brinzolamide ophthalmic)
GENERALLY AVOID: Following ophthalmic administration, brinzolamide and dorzolamide are systemically absorbed and may have additive pharmacologic effects with other, systemically administered carbonic anhydrase inhibitors. The risk of adverse effects such as drowsiness, paresthesia, tinnitus, electrolyte imbalance, metabolic acidosis, and gastrointestinal disturbances may be increased.
MANAGEMENT: The concomitant use of ocular and systemic carbonic anhydrase inhibitors is not recommended.
References (2)
- (2001) "Product Information. Azopt (brinzolamide ophthalmic)." Alcon Laboratories Inc
- (2001) "Product Information. Trusopt (dorzolamide ophthalmic)." Merck & Co., Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Carbonic anhydrase inhibitor ophthalmics
Therapeutic duplication
The recommended maximum number of medicines in the 'carbonic anhydrase inhibitor ophthalmics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'carbonic anhydrase inhibitor ophthalmics' category:
- Azopt (brinzolamide ophthalmic)
- Neptazane (methazolamide)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Xalatan
Xalatan (latanoprost) is used to treat certain types of glaucoma. Includes Xalatan side effects ...
Lumigan
Lumigan is used to treat open angle glaucoma. Learn about side effects, interactions and indications.
Botox
Botox is used to treat chronic migraines, excessive sweating, bladder conditions, eye muscle ...
Cosopt
Cosopt reduces the amount of fluid in the eye and is used to treat glaucoma. Learn about side ...
Combigan
Combigan (brimonidine and timolol) is used to treat glaucoma or ocular hypertension. Includes ...
Alphagan P
Alphagan P is used to treat glaucoma or ocular hypertension (high pressure inside the eye). Learn ...
Vyzulta
Vyzulta is used for glaucoma, open angle, glaucoma/intraocular hypertension
Rhopressa
Rhopressa is used for glaucoma, open angle, intraocular hypertension
Simbrinza
Simbrinza (brimonidine and brinzolamide) is used to treat open-angle glaucoma or ocular ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.