Drug Interaction Report
5 potential interactions and/or warnings found for the following 2 drugs:
- darolutamide
- Prevpac (amoxicillin / clarithromycin / lansoprazole)
Interactions between your drugs
clarithromycin lansoprazole
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole), Prevpac (amoxicillin / clarithromycin / lansoprazole)
Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
clarithromycin darolutamide
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole), darolutamide
Clarithromycin may significantly increase the blood levels of darolutamide. This can increase the risk and/or severity of side effects such as fatigue, high blood pressure, decreased white blood cell counts, and liver problems. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
amoxicillin clarithromycin
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole), Prevpac (amoxicillin / clarithromycin / lansoprazole)
Information for this minor interaction is available on the professional version.
Drug and food interactions
darolutamide food
Applies to: darolutamide
Food helps with the absorption of darolutamide into the blood stream. You should take this medication with food as directed.
clarithromycin food
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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