Drug Interaction Report
7 potential interactions and/or warnings found for the following 2 drugs:
- clobazam
- Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Interactions between your drugs
ethinyl estradiol cloBAZam
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone), clobazam
CloBAZam may reduce the blood levels and effects of ethinyl estradiol. If you are using birth control pills or another hormone-type contraceptive such as a patch, shot, vaginal ring or implant, you should talk to your doctor before taking cloBAZam. You may need an alternative or additional method of birth control during and for at 28 days after treatment with cloBAZam in order to avoid an unintended pregnancy. Let your doctor know if you experience bleeding outside of your menstrual cycle, since it may indicate reduced effectiveness of ethinyl estradiol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
norethindrone cloBAZam
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone), clobazam
CloBAZam may reduce the blood levels and effects of norethindrone. If you are using birth control pills or another hormone-type contraceptive such as a patch, shot, vaginal ring or implant, you should talk to your doctor before taking cloBAZam. You may need an alternative or additional method of birth control during and for at 28 days after treatment with cloBAZam in order to avoid an unintended pregnancy. Let your doctor know if you experience bleeding outside of your menstrual cycle, since it may indicate reduced effectiveness of norethindrone. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
norethindrone food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
cloBAZam food
Applies to: clobazam
Alcohol can increase the nervous system side effects of cloBAZam such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cloBAZam. Do not use more than the recommended dose of cloBAZam, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
ethinyl estradiol food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
norethindrone food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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