Drug Interaction Report

Talk to your doctor before using dienogest together with griseofulvin. Combining these medications may decrease the blood levels and effects of dienogest. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. Because use of griseofulvin has been associated with birth defects, it is particularly important that you do not become pregnant during treatment. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. Your doctor may also be able to prescribe alternatives that do not interact. If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Griseofulvin may reduce the blood levels and effects of estradiol. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

You may be advised to take griseofulvin with a fatty meal to increase its absorption into your body. This will make it easier for your body to absorb the medication. The combination of alcohol and griseofulvin may cause flushing and a fast heart rate. Use alcohol cautiously during treatment with griseofulvin.

Grapefruit juice may increase the blood levels of certain medications such as dienogest. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with dienogest. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

Information for this minor interaction is available on the professional version.