Drug Interaction Report

Clotrimazole may increase the blood levels and effects of atazanavir. This may increase the risk and/or severity of side effects such as jaundice, kidney stones, gallstones, high blood sugar, diabetes, and irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop yellowing of the skin or eyes, pain in your side or lower back, painful urination, blood in your urine, abdominal pain or tenderness, or sudden dizziness, lightheadedness, fainting, or a slow heart rate during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Using cobicistat together with clotrimazole may increase the blood levels and side effects of one or both medications. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food can enhance the levels of atazanavir in your body. To ensure maximal oral absorption, atazanavir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.