Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- azithromycin
- bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus
Interactions between your drugs
azithromycin lactobacillus acidophilus
Applies to: azithromycin, bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus
ADJUST DOSING INTERVAL: Coadministration of oral probiotic preparations with oral antibiotics may reduce the efficacy of the probiotic. It has been theorized that concomitant antibiotics may kill the live organisms found in lactobacillus-, bacillus coagulans-, and bifidobacteria-containing oral probiotic preparations. However, the clinical significance of the interaction has not been established.
MANAGEMENT: Although data are limited, it may be prudent to advise patients to take oral probiotics at least 1 to 2 hours before or after an oral antibiotic.
References (3)
- Clarion Brands, Inc. (2020) Florajen Probiotics. https://www.florajen.com/products/florajen-women
- Xiao JZ, Takahashi S, Odamaki T, Yaeshima T, iwatsuki k (2010) "Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market." Biosci Biotechnol Biochem, 74, p. 336-42
- dwyer a (2024) Taking probiotics with antibiotics https://www.optibacprobiotics.com/learning-lab/in-depth/general-health/probiotics-with-antibiotics
azithromycin bifidobacterium infantis
Applies to: azithromycin, bifidobacterium infantis / lactobacillus acidophilus / streptococcus thermophilus
ADJUST DOSING INTERVAL: Coadministration of oral probiotic preparations with oral antibiotics may reduce the efficacy of the probiotic. It has been theorized that concomitant antibiotics may kill the live organisms found in lactobacillus-, bacillus coagulans-, and bifidobacteria-containing oral probiotic preparations. However, the clinical significance of the interaction has not been established.
MANAGEMENT: Although data are limited, it may be prudent to advise patients to take oral probiotics at least 1 to 2 hours before or after an oral antibiotic.
References (3)
- Clarion Brands, Inc. (2020) Florajen Probiotics. https://www.florajen.com/products/florajen-women
- Xiao JZ, Takahashi S, Odamaki T, Yaeshima T, iwatsuki k (2010) "Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market." Biosci Biotechnol Biochem, 74, p. 336-42
- dwyer a (2024) Taking probiotics with antibiotics https://www.optibacprobiotics.com/learning-lab/in-depth/general-health/probiotics-with-antibiotics
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Augmentin
Augmentin is a prescription antibiotic combining amoxicillin and clavulanate to treat bacterial ...
Bactrim
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary ...
Botox
Botox is used to treat chronic migraines, excessive sweating, bladder conditions, eye muscle ...
Keflex
Keflex (cephalexin) is used to treat infections caused by bacteria, including respiratory ...
Ventolin
Ventolin is used for asthma, acute, asthma, maintenance, bronchiectasis, bronchospasm prophylaxis ...
Ventolin HFA
Ventolin HFA (albuterol) is used to treat or prevent breathing problems in patients who have asthma ...
Mucinex
Mucinex (guaifenesin) is used to relieve the symptoms of cough and loosen mucus in the chest ...
Cipro
Cipro (ciprofloxacin) is a fluoroquinolone antibiotic used to treat bacterial infections. Learn ...
Zithromax
Zithromax (azithromycin) treats infections caused by bacteria, such as respiratory infections, skin ...
Advair Diskus
Advair is used to prevent asthma attacks and to treat COPD. Learn about side effects, interactions ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.